A Photographic series that expresses the abstract states of myself, towards the question of existence that results from being surrounded by expectations of both surrender and freedom of expression, this series focuses on my own subjectivities in order to bring back memories of almost forgotten feelings and make them clear once more.
การที่เติบโตมาจากครอบครัวที่คาดหวังในตัวเรา ที่สมาชิกคาดหวังในตัวเราไม่เหมือนกัน ถ้าเราทำแบบใดแบบหนึ่งที่คนใดคนหนึ่งต้องการอีกคนจะไม่พอใจ จนเราเกิดสงสัยว่าเราต้องเป็นแบบไหน เมื่อเข้ามาอยู่ในสังคมใหม่ทำให้เราตั้งคำถามกับตนเองเมื่อเข้าหาผู้คนว่าเราต้องเป็นไปแบบที่เขาต้องการหรือเปล่าเราถึงจะเข้าถึงเขาได้ ทำให้เราสับสนกับตัวเองและต้องสร้างตัวตนใหม่ไปตามที่คนคนนั้นพอใจ จนเราเองเริ่มเกิดคำถามว่าจริงๆแล้วตัวตนของเราจริงๆเป็นแบบไหน
คณะครุศาสตร์อุตสาหกรรมและเทคโนโลยี
This project presents the development of a single-frequency GPS-based total electron content measurement tool. It applies theories related to total electron content in the ionospheric layer and the measurement of total electron content using GPS time delay to design the single-frequency GPS total electron content measurement tool. The tool consists of an antenna, a single-frequency GPS satellite receiver, a data processing unit for evaluating and calculating total electron content, and a display unit for showing total electron content data. The performance of the single-frequency GPS total electron content measurement tool is tested by comparing it with total electron content data obtained from the International Reference Ionosphere (IRI) model, which is a global reference model for electron content. The tool is also put to practical use. The results of the comparison and practical applications conclude that the single-frequency GPS-based total electron content measurement tool can be effectively utilized, with the difference from the IRI model being 50 TECU
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.
คณะอุตสาหกรรมอาหาร
Tepache is a traditional Mexican fermented beverage commonly made using pineapple peels, which naturally contain sugars and the enzyme bromelain. These components contribute to its distinctive aroma and unique flavor. This project aims to develop a health-enhancing tepache by fermenting pineapple peels with probiotic yeast and lactic acid bacteria. Additionally, prebiotics, including inulin and xylo-oligosaccharides, are incorporated as nutrients to support probiotic growth. The resulting synbiotic tepache promotes gut microbiota balance, exhibits antioxidant properties, and enhances the immune system, making it a functional and beneficial beverage for consumers.