The purpose of this invention is to develop a forest fire prevention agent that has the ability to prevent long-term forest fires, not only to suppress forest fires or prevent forest fires from spreading widely, but to prevent them from starting to catch fire from the beginning. It can prevent forest fires comprehensively and can be prevented for a long time during the peak forest fire period or the dry season, which is about 3-4 months. There are no residues or minimal residues without causing harm to the surrounding environment under the specified standards. Emphasis is placed on the use of raw materials, equipment, and chemicals that can be easily found in Thailand. This includes using the value of production costs as low as possible. This makes it suitable for use in large quantities for spraying and protecting forest areas in forest areas that are prone to fire. Estimated average for pollution caused by forest fires include particulate matter (PM), including PM2.5, PM10, carbon monoxide (CO), carbon dioxide, carbon dioxide, and carbon dioxide, Nitrogendioxide, VOC etc.
ป่าไม้เป็นทรัพยากรธรรมชาติที่มีคุณค่าต่อมนุษย์มากมาย ป่าไม้เป็นแหล่งปัจจัยพื้นฐานสี่ประการที่ทำให้มนุษย์สามารถดำรงชีวิตอยู่ได้ นอกจากนี้ป่าไม้ยังเป็นที่อยู่ของสิ่งมีชีวิตต่างๆรวมถึงสัตว์ป่าและพืชพรรณนานาชนิด ปัญหาไฟป่าเป็นอีกปัจจัยที่ส่งผลให้ทรัพยากรป่าไม้เสื่อมโทรมลงอย่างมาก ส่งผลให้ป่าไม้ไม่สามารถฟื้นตัวได้ทันตามวัฏจักรธรรมชาติ ปัจจุบันประเทศไทยได้สูญเสียพื้นที่ป่าไปเป็นจำนวนมากกว่า 1000000 ไร่ในสิบปีหลังสุด และผลกระทบจากไฟป่าทำให้เกิดปัญหาหมอกควันกระจายท้่วไปในบริเวณภาคเหนือ ภาคกลาง และตะวันออกเฉียงเหนือของประเทศ ทำให้ประชาชนจำนวนมากประสบปัญหาโรคระบบทางเดินหายใจ นวัตกรรมนี้จึงถูกสร้างขึ้นเพื่อต้องการลดปัญหาไฟป่าและปกป้องคลุมครองพื้นที่ป่าของประเทศ
คณะแพทยศาสตร์
Background: The RGL3 gene plays a role in key signal transduction pathways and has been implicated in hypertension risk through the identification of a copy number variant deletion in exon 6. Genome-wide association studies have highlighted RGL3 as associated with hypertension, providing insights into the genetic underpinnings of the condition and its protective effects on cardiovascular health. Despite these findings, there is a lack of data that confirms the precise role of RGL3 in hypertension. Additionally, the functional impact of certain variants, particularly those classified as variants of uncertain significance, remains poorly understood. Objectives: This study aims to analyze alterations in the RGL3 protein structure caused by mutations and validate the location of the ligand binding sites. Methods: Clinical variants of the RGL3 gene were obtained from NCBI ClinVar. Variants of uncertain significance and likely benign were analyzed. Multiple sequence alignment was conducted using BioEdit v7.7.1. AlphaFold 2 predicted the wild-type and mutant 3D structures, followed by quality assessment via PROCHECK. Functional domain analysis of RasGEF, RASGEF_NTER, and RA domains was performed, and BIOVIA Discovery Studio Visualizer 2024 was used to evaluate structural and physicochemical changes. Results: The analysis of 81 RGL3 variants identified 5 likely benign and 76 variants of uncertain significance (VUS), all of which were missense mutations. Structural modeling using AlphaFold 2 revealed three key domains: RasGEF_NTER, RasGEF, and RA, where mutations induced conformational changes. Ramachandran plot validation confirmed 79.7% of residues in favored regions, indicating an overall reliable structure. Moreover, mutations within RasGEF and RA domains altered polarity, charge, and stability, suggesting potential functional disruptions. These findings provide insight into the structural consequences of RGL3 mutations, contributing to further functional assessments. Discussion & Conclusion: The identified RGL3 mutations induced physicochemical alterations in key domains, affecting charge, polarity, hydrophobicity, and flexibility. These changes likely disrupt interactions with Ras-like GTPases, impairing GDP-GTP exchange and cellular signaling. Structural analysis highlighted mutations in RasGEF and RA domains that may interfere with activation states, potentially affecting protein function and stability. These findings suggest that mutations in RGL3 could have functional consequences, emphasizing the need for further molecular and functional studies to explore their pathogenic potential.
วิทยาลัยนวัตกรรมการผลิตขั้นสูง
The research on improving the strength of solid electrolytes aims to enhance the properties of solid electrolyte materials produced from cement and additives that help develop the cement structure to generate electricity. The main components include sodium chloride (NaCl) and graphite, which contribute to the material’s ability to generate a weak electrical current. The objective is to develop an electricity-generating flooring material. This study involves preparing a mixture of cement, water, sodium chloride (NaCl), and graphite to enhance the material’s electrical conductivity. It is highly anticipated that this research will lead to the development of concrete flooring capable of generating electricity and can be further expanded for future applications.
คณะเทคโนโลยีการเกษตร
This project presents a design and management approach for agricultural land in Kanchanaburi Province. The case study area is situated in Wangdong Subdistrict, Mueang Kanchanaburi District, covering an area of approximately 18 rai (7.2 acres). As the user seeks a simplified lifestyle in the countryside, surrounded by nature, the design aligns with this vision of simplicity and sustainability. The land is systematically allocated to optimize the benefits for both daily living and agricultural industry development. The crop cultivation zones are designed to suit the local climate and plant varieties, ensuring high-quality yields for continuous utilization. Meanwhile, the livestock zones are clearly delineated to maintain balance and organization. This approach not only ensures food security and income generation but also promotes a lifestyle that harmonizes with nature, minimizes environmental impact, and supports the long-term development of an efficient and eco-friendly agricultural industry. Comprehensive attention is given to the positioning of various zones, considering wind direction and sunlight exposure. Additionally, the design undergoes a rigorous drafting and review process to ensure the optimal outcomes for the land's utilization.