This study focuses on formula development and properties analysis of collagen-fortified kombucha jelly in terms of taste, appearance, and benefits to create a novel product that meets the needs of the health and beauty beverage market. Sensory testing was conducted to evaluate the quality and consumer satisfaction.
ปัจจุบันผู้บริโภคให้ความสำคัญกับผลิตภัณฑ์เพื่อสุขภาพและความงามมากขึ้น โดยเฉพาะสินค้าที่รับประทานง่ายและมีคุณค่าทางโภชนาการ การผลิต เจลลี่คอมบูชาเสริมคอลลาเจน จึงเป็นทางเลือกใหม่ที่รวมคุณสมบัติของ คอมบูชา ซึ่งอุดมด้วยจุลินทรีย์โปรไบโอติกและสารต้านอนุมูลอิสระที่ดีต่อระบบย่อยอาหาร กับ คอลลาเจน ที่ช่วยเสริมสร้างความยืดหยุ่นของผิว ผลิตภัณฑ์นี้ออกแบบให้อยู่ในรูปแบบเจลลี่เพื่อความสะดวกในการบริโภคและพกพา คอมบูชาเป็นชาหมักที่ได้รับความนิยมมายาวนาน มีสารโพรไบโอติกช่วยปรับสมดุลลำไส้และเสริมภูมิคุ้มกัน อีกทั้งยังมีสารต้านอนุมูลอิสระที่ช่วยลดความเสี่ยงของโรคต่างๆ เช่น โรคทางเดินอาหารและระบบภูมิคุ้มกันบกพร่อง ในขณะเดียวกัน คอลลาเจนเป็นโปรตีนสำคัญที่ช่วยบำรุงผิวพรรณ ผม และเล็บ การผสมผสานทั้งสองเข้าด้วยกันในรูปแบบเจลลี่ ทำให้สามารถบริโภคได้ง่ายขึ้นและเสริมประโยชน์ต่อสุขภาพแบบองค์รวม
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
The forest firefighting suit consists of the following components and uses: The forest firefighting suit is designed and developed to be suitable for the behavior of the officers and the conditions of the work area, consisting of a shirt and pants. The material used in the sewing of the suit is aramid fabric, which has the property of being able to prevent the spread of fire, to prevent the officers from burning while performing their duties in the event that the forest fire spreads close to them, which is different from the current suits that cannot prevent fires. The shirt is designed with a mesh on the side of the body to release internal heat so that air can circulate well. The sleeves at the elbows have a support point to prevent contact with the ground or obstacles. The collar has a slot for a portable fan and a fan air circulation channel on the back, which can be turned on while performing forest firefighting duties, helping to prevent the body temperature from getting too hot, reducing the risk of heatstroke. When the fan battery runs out, it can be removed for charging and put back in when needed. The pants are designed with mesh on the inside or in blind spots to release internal heat so that air can circulate well. The pants at the knees have a support point to prevent contact with the ground or obstacles. The forest firefighting suit, consisting of a shirt and pants, has been designed and developed to be able to be produced domestically, reducing imports from abroad
คณะเทคโนโลยีการเกษตร
The research aims to develop chili Thai commercial varieties for resistance to anthracnose and Pepper yellow leaf curl virus disease. The varieties allowing farmer to reduce the use of chemical pesticides for disease and pest control, also increases productivity and lowers production costs for farmers. The development new varieties are under studied of undergraduate, master's, and doctoral students by using conventional and molecular plant breeding. The new chili varieties were released to farmer and commercial companies for development for Thai commercial seed industry.
คณะแพทยศาสตร์
Background: The RGL3 gene plays a role in key signal transduction pathways and has been implicated in hypertension risk through the identification of a copy number variant deletion in exon 6. Genome-wide association studies have highlighted RGL3 as associated with hypertension, providing insights into the genetic underpinnings of the condition and its protective effects on cardiovascular health. Despite these findings, there is a lack of data that confirms the precise role of RGL3 in hypertension. Additionally, the functional impact of certain variants, particularly those classified as variants of uncertain significance, remains poorly understood. Objectives: This study aims to analyze alterations in the RGL3 protein structure caused by mutations and validate the location of the ligand binding sites. Methods: Clinical variants of the RGL3 gene were obtained from NCBI ClinVar. Variants of uncertain significance and likely benign were analyzed. Multiple sequence alignment was conducted using BioEdit v7.7.1. AlphaFold 2 predicted the wild-type and mutant 3D structures, followed by quality assessment via PROCHECK. Functional domain analysis of RasGEF, RASGEF_NTER, and RA domains was performed, and BIOVIA Discovery Studio Visualizer 2024 was used to evaluate structural and physicochemical changes. Results: The analysis of 81 RGL3 variants identified 5 likely benign and 76 variants of uncertain significance (VUS), all of which were missense mutations. Structural modeling using AlphaFold 2 revealed three key domains: RasGEF_NTER, RasGEF, and RA, where mutations induced conformational changes. Ramachandran plot validation confirmed 79.7% of residues in favored regions, indicating an overall reliable structure. Moreover, mutations within RasGEF and RA domains altered polarity, charge, and stability, suggesting potential functional disruptions. These findings provide insight into the structural consequences of RGL3 mutations, contributing to further functional assessments. Discussion & Conclusion: The identified RGL3 mutations induced physicochemical alterations in key domains, affecting charge, polarity, hydrophobicity, and flexibility. These changes likely disrupt interactions with Ras-like GTPases, impairing GDP-GTP exchange and cellular signaling. Structural analysis highlighted mutations in RasGEF and RA domains that may interfere with activation states, potentially affecting protein function and stability. These findings suggest that mutations in RGL3 could have functional consequences, emphasizing the need for further molecular and functional studies to explore their pathogenic potential.