The species Enterococcus lactis is closely related to E. faecium and is known for its beneficial and probiotic effects. In this study, strain RRS4 was isolated from Raphanus sativus Linn. and identified based on both phenotypic and genotypic characteristics. Strain RRS4 exhibited cell viability in environments with 2-8% NaCl, pH ranging from 4 to 9, and temperatures between 4°C and 45°C. Through comprehensive genomic analysis, strain RRS4 was confirmed to be E. lactis. E. lactis RRS4 demonstrated inhibitory effects against Vancomycin-resistant E. faecalis JCM 5803. Safety assessments via in silico methods, including KEGG annotation, indicated the absence of virulent and undesirable genes in E. lactis RRS4. VirulenceFinder analysis aligned virulence-related genes with those from three strains of E. lactis and four strains of E. faecium. While antibiotic resistance genes were found to be conserved, they did not correlate with key pathogenicity traits. Furthermore, safety evaluations highlighted that E. lactis RRS4 is generally safe, despite the presence of genes associated with antibiotic resistance. Lastly, we propose guidelines for assessing the safety of microbial strains using whole-genome analysis. These findings represent advancements in probiotic research.
ปัจจุบันมีงานวิจัยเกี่ยวกับโพรไบโอติกส์เพิ่มมากขึ้น เนื่องจากโพรไบโอติกส์มีประโยชน์ต่อสุขภาพมนุษย์โดยเฉพาะระบบทางเดินอาหาร เช่น ช่วยการปรับสมดุลลำไส้ กระตุ้นการทำงานของ ระบบภูมิคุ้มกัน ส่งเสริมกระบวนการย่อยอาหาร ลดระดับคอเลสเตอรอล ถึงแม้โพรไบโอติกส์จะมีประโยชน์มากแต่ก็ควรบริโภคในปริมาณที่เหมาะสม หากได้รับมากเกินไปอาจส่งผลเสียต่อร่างกายได้ โดยโพรไบโอติกส์สามารถพบได้ทั้งในแบคทีเรียและยีสต์ที่มีชีวิตหลายชนิด แต่ชนิดที่พบมากที่สุดและถูกใช้ในผลิตภัณฑ์อาหารเสริมมักจะอยู่ในกลุ่มของแบคทีเรียกรดแลคติก
คณะวิทยาศาสตร์
Development of Hand Cream from Murraya Extract Using an Eco-Friendly Extraction Process. This research focuses on extracting active compounds from Murraya paniculata using a water-based, environmentally friendly method. The extract exhibits outstanding antibacterial properties and anti-oxidant. It is incorporated into a hand cream formulation.
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
From the current situation and uncertainty; leads to the concept of food security. It is the application of innovation and technology to create high productivity in a limited area. The unused buildings in urban areas were renovated for planting, created as a learning area for planting in urban area. The different methods of growing plants were presented. There are 35 planting innovations for disseminating knowledge, to create food security, self-reliant, supports sustainable living.
คณะเทคโนโลยีการเกษตร
Climate change affects agricultural systems worldwide, including Thailand, and may lead to reduced crop yields, impacting food security. Bambara groundnut is a crop with the potential to adapt to changing environments and can thrive in areas with limited resources. This research aims to study the impact of climate change on Bambara groundnut yields in Thailand using the DSSAT (Decision Support System for Agrotechnology Transfer) model, an important tool for predicting plant growth under various environmental conditions. This study utilizes climate data, soil composition, and genetic information of Bambara groundnut to simulate and analyze yield trends under future climate scenarios. Four study areas in Thailand were selected: Songkhla, Lampang, Yasothon, and Saraburi. The CSM-CROPGRO-Bambara groundnut model was used to assess the impact of changing temperature and rainfall on the growth and yield of Bambara groundnut. The results of this study are expected to provide farmers and researchers with valuable information for planning cultivation and managing peanut production in response to climate change. Additionally, the findings can help formulate policy guidelines to promote the cultivation of climate-resilient crops and support the country's food security.