The species Enterococcus lactis is closely related to E. faecium and is known for its beneficial and probiotic effects. In this study, strain RRS4 was isolated from Raphanus sativus Linn. and identified based on both phenotypic and genotypic characteristics. Strain RRS4 exhibited cell viability in environments with 2-8% NaCl, pH ranging from 4 to 9, and temperatures between 4°C and 45°C. Through comprehensive genomic analysis, strain RRS4 was confirmed to be E. lactis. E. lactis RRS4 demonstrated inhibitory effects against Vancomycin-resistant E. faecalis JCM 5803. Safety assessments via in silico methods, including KEGG annotation, indicated the absence of virulent and undesirable genes in E. lactis RRS4. VirulenceFinder analysis aligned virulence-related genes with those from three strains of E. lactis and four strains of E. faecium. While antibiotic resistance genes were found to be conserved, they did not correlate with key pathogenicity traits. Furthermore, safety evaluations highlighted that E. lactis RRS4 is generally safe, despite the presence of genes associated with antibiotic resistance. Lastly, we propose guidelines for assessing the safety of microbial strains using whole-genome analysis. These findings represent advancements in probiotic research.
ปัจจุบันมีงานวิจัยเกี่ยวกับโพรไบโอติกส์เพิ่มมากขึ้น เนื่องจากโพรไบโอติกส์มีประโยชน์ต่อสุขภาพมนุษย์โดยเฉพาะระบบทางเดินอาหาร เช่น ช่วยการปรับสมดุลลำไส้ กระตุ้นการทำงานของ ระบบภูมิคุ้มกัน ส่งเสริมกระบวนการย่อยอาหาร ลดระดับคอเลสเตอรอล ถึงแม้โพรไบโอติกส์จะมีประโยชน์มากแต่ก็ควรบริโภคในปริมาณที่เหมาะสม หากได้รับมากเกินไปอาจส่งผลเสียต่อร่างกายได้ โดยโพรไบโอติกส์สามารถพบได้ทั้งในแบคทีเรียและยีสต์ที่มีชีวิตหลายชนิด แต่ชนิดที่พบมากที่สุดและถูกใช้ในผลิตภัณฑ์อาหารเสริมมักจะอยู่ในกลุ่มของแบคทีเรียกรดแลคติก
คณะเทคโนโลยีการเกษตร
This project presents a design and management approach for agricultural land in Kanchanaburi Province. The case study area is situated in Wangdong Subdistrict, Mueang Kanchanaburi District, covering an area of approximately 18 rai (7.2 acres). As the user seeks a simplified lifestyle in the countryside, surrounded by nature, the design aligns with this vision of simplicity and sustainability. The land is systematically allocated to optimize the benefits for both daily living and agricultural industry development. The crop cultivation zones are designed to suit the local climate and plant varieties, ensuring high-quality yields for continuous utilization. Meanwhile, the livestock zones are clearly delineated to maintain balance and organization. This approach not only ensures food security and income generation but also promotes a lifestyle that harmonizes with nature, minimizes environmental impact, and supports the long-term development of an efficient and eco-friendly agricultural industry. Comprehensive attention is given to the positioning of various zones, considering wind direction and sunlight exposure. Additionally, the design undergoes a rigorous drafting and review process to ensure the optimal outcomes for the land's utilization.
คณะศิลปศาสตร์
"Niyom Thai" represents health-centric footwear adorned with traditional Thai patterns, embodying an innovative approach to sustainable development tailored to the current needs of local communities. These shoes utilize natural materials to mitigate fatigue and integrate safety technologies, including location tracking via a mobile application and heart rate monitoring. This addresses the aspects of convenience and well-being in both daily life and travel
คณะอุตสาหกรรมอาหาร
This black rice yogurt combines Trio Probiotic popping pearls and healthy rice cereal, rich in anthocyanins that help slow down bodily aging. It contains 3 types of probiotics to support gut balance and enhance digestive efficiency. This zero-waste product repurposes rice residue from the production process into nutritious cereal, offering a delicious and health-packed experience in one cup.