The species Enterococcus lactis is closely related to E. faecium and is known for its beneficial and probiotic effects. In this study, strain RRS4 was isolated from Raphanus sativus Linn. and identified based on both phenotypic and genotypic characteristics. Strain RRS4 exhibited cell viability in environments with 2-8% NaCl, pH ranging from 4 to 9, and temperatures between 4°C and 45°C. Through comprehensive genomic analysis, strain RRS4 was confirmed to be E. lactis. E. lactis RRS4 demonstrated inhibitory effects against Vancomycin-resistant E. faecalis JCM 5803. Safety assessments via in silico methods, including KEGG annotation, indicated the absence of virulent and undesirable genes in E. lactis RRS4. VirulenceFinder analysis aligned virulence-related genes with those from three strains of E. lactis and four strains of E. faecium. While antibiotic resistance genes were found to be conserved, they did not correlate with key pathogenicity traits. Furthermore, safety evaluations highlighted that E. lactis RRS4 is generally safe, despite the presence of genes associated with antibiotic resistance. Lastly, we propose guidelines for assessing the safety of microbial strains using whole-genome analysis. These findings represent advancements in probiotic research.
ปัจจุบันมีงานวิจัยเกี่ยวกับโพรไบโอติกส์เพิ่มมากขึ้น เนื่องจากโพรไบโอติกส์มีประโยชน์ต่อสุขภาพมนุษย์โดยเฉพาะระบบทางเดินอาหาร เช่น ช่วยการปรับสมดุลลำไส้ กระตุ้นการทำงานของ ระบบภูมิคุ้มกัน ส่งเสริมกระบวนการย่อยอาหาร ลดระดับคอเลสเตอรอล ถึงแม้โพรไบโอติกส์จะมีประโยชน์มากแต่ก็ควรบริโภคในปริมาณที่เหมาะสม หากได้รับมากเกินไปอาจส่งผลเสียต่อร่างกายได้ โดยโพรไบโอติกส์สามารถพบได้ทั้งในแบคทีเรียและยีสต์ที่มีชีวิตหลายชนิด แต่ชนิดที่พบมากที่สุดและถูกใช้ในผลิตภัณฑ์อาหารเสริมมักจะอยู่ในกลุ่มของแบคทีเรียกรดแลคติก
คณะบริหารธุรกิจ
Evenly Distributed Temperature Controlled Medical Refrigerator is the medical refrigerator which equipped with specialized control system to control the cold air distribution within the chamber to have the same temperature along the different height within the chamber.
คณะวิศวกรรมศาสตร์
Nowadays, rail transportation has a significant impact on people's lives and economic growth. Consequently, the number of rail systems being built around our country has dramatically increased. This process causes various types of pollution, such as noise and rail-way vibration, which can badly affect the life of citizens who live nearby. The most popular way to solve this problem recently is to decrease the noise from the sound source or to adjust the vibration by attaching a Track Damper to the railway. This technique is being used in many countries especially in Europe and Australia because it is cheap and has high efficiency. The key piece called Track Dampers are made by AUT company’s Thailand for a period of time. The company produces Track Dampers for the owner of the technology so as to sell more than 300,000 pieces of it overseas. Furthermore, the demand of Track Dampers grows as the railway systems expand. Unfortunately, the imported synthetic materials, which are used to create Track Dampers, are made from environmentally unfriendly sources. As a result, this research aims to develop the product to be environmentally-safe by replacing some imported materials with Thai’s local content; which are natural rubber and rubber crumbs. Furthermore, the product will be added value by mounting with embedded sensors for real-time monitoring of track vibration, noise, and rail temperature. All embedded devices developed will sense, collect, and automatically send to cloud by wireless technology platform. The AI and IOT platform will also be developed for safety, security, and maintenance proposed of railway track system. However, in conducting research, there will be close collaboration with AUT company through design, production, and testing. The outcome of this research is to upgrade AUT company from tier 2 manufacturer (TRL 8-9) to tier 1 manufacturer (TRL 7-8) which will be served the Thailand competitiveness enhancing strategic goal.
คณะวิศวกรรมศาสตร์
Due to the modern urban system's high demand for stable electricity supply, underground cable power transmission has been increasingly adopted as a replacement for overhead power transmission. However, underground cable transmission still faces several operational challenges, such as significantly higher investment costs compared to overhead transmission, prolonged repair times in the event of system failures, limited fault analysis capabilities, and restricted capacity for additional load handling. This research project is designed to study the issues associated with the 22 kV XLPE underground cable system by utilizing the polarization and depolarization current analysis technique, a modern insulation diagnostic method.