This research aims to study the waste management process of horse manure, the production process of organic fertilizer from horse waste, and opinions on the use of innovative organic fertilizer from horse manure. A mixed-method approach, combining qualitative and quantitative research, is employed. The organic fertilizer is produced from horse manure, which is a waste that incurs disposal costs. Through the fermentation process, it is transformed into an environmentally friendly fertilizer containing essential nutrients beneficial to plants. According to the laboratory analysis of the organic fertilizer conducted by the Soil Science Laboratory, Faculty of Agricultural Technology, King Mongkut's Institute of Technology Ladkrabang, it was found that organic fertilizer from horse manure contains essential nutrients for plant growth, including macronutrients, secondary nutrients, and micronutrients. This reflects the potential of horse waste management, the production process of organic fertilizer from horse manure, the efficiency of the organic fertilizer, and strategies for adding value to expand its commercialization.
ปัจจุบันกีฬาขี่ม้าในประเทศไทยได้รับความนิยม และเกิดฟาร์มเลี้ยงม้าในประเทศไทยมากขึ้น ส่งผลให้เกิดปัญหาการจัดการของเสียจากม้า โดยม้าแต่ละตัวผลิตมูลเฉลี่ย 18-23 กิโลกรัมต่อวัน หรือประมาณ 1 ตันต่อเดือน หากไม่มีการจัดการที่เหมาะสม อาจก่อให้เกิดปัญหาด้านสิ่งแวดล้อม เช่น กลิ่นเหม็น การแพร่กระจายของเชื้อโรค และข้อร้องเรียนจากชุมชนโดยรอบ เจ้าของฟาร์มต้องเสียค่าใช้จ่ายในการกำจัดมูลม้า แนวทางหนึ่งที่ช่วยลดปัญหาคือการนำของเสียจากม้ามาผลิตเป็นปุ๋ยอินทรีย์ ซึ่งเป็นกระบวนการที่ช่วยลดของเสียและเพิ่มมูลค่าทางเศรษฐกิจ เพื่อพัฒนาคุณภาพปุ๋ยอินทรีย์ สามารถนำสารเร่งหมักมาใช้เพื่อลดระยะเวลาการหมัก และเสริมแหนแดงเพื่อเพิ่มปริมาณไนโตรเจนในปุ๋ย ซึ่งช่วยให้ได้ปุ๋ยที่มีประสิทธิภาพสูงขึ้นและสามารถนำไปใช้เชิงพาณิชย์ สร้างรายได้ให้กับเจ้าของฟาร์มและเป็นมิตรกับสิ่งแวดล้อม
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
This app encourages users to clean by turning it into a fun game. Users can choose cleaning tasks, track dust levels, and earn reward points, making the cleaning process more engaging and enjoyable.
คณะวิศวกรรมศาสตร์
This study focuses on the use of ceramic tile powder as a cement replacement material in concrete at an appropriate ratio. The objective is to investigate the properties of replacing cement with tile powder and to determine the optimal mixing ratio of tile powder in cement mortar that can yield properties equivalent to or superior to conventional cement mortar. The experiment involved preparing cement mortar samples by replacing cement with two types of ceramic tile powder waste from tile manufacturing plants: waste tile powder and rectified tile powder. The mixing process was divided into two parts: Part 1 used a cement and tile powder ratio, while Part 2 used the results of the strength analysis from Part 1 to adjust the ratio accordingly. Various properties were tested, including specific gravity, normal consistency, setting time, tensile strength, and compressive strength. The results of the study revealed that replacing of cement with rectified tile powder provided the highest tensile and compressive strength, comparable to that of conventional cement mortar. Therefore, the use of ceramic tile powder as a replacement can enhance compressive strength while reducing cement usage, which has positive environmental implications by decreasing greenhouse gas emissions from cement production. Furthermore, this approach promotes the effective use of waste materials from the ceramic industry, contributing to the sustainability of the construction industry.
คณะแพทยศาสตร์
Background: The RGL3 gene plays a role in key signal transduction pathways and has been implicated in hypertension risk through the identification of a copy number variant deletion in exon 6. Genome-wide association studies have highlighted RGL3 as associated with hypertension, providing insights into the genetic underpinnings of the condition and its protective effects on cardiovascular health. Despite these findings, there is a lack of data that confirms the precise role of RGL3 in hypertension. Additionally, the functional impact of certain variants, particularly those classified as variants of uncertain significance, remains poorly understood. Objectives: This study aims to analyze alterations in the RGL3 protein structure caused by mutations and validate the location of the ligand binding sites. Methods: Clinical variants of the RGL3 gene were obtained from NCBI ClinVar. Variants of uncertain significance and likely benign were analyzed. Multiple sequence alignment was conducted using BioEdit v7.7.1. AlphaFold 2 predicted the wild-type and mutant 3D structures, followed by quality assessment via PROCHECK. Functional domain analysis of RasGEF, RASGEF_NTER, and RA domains was performed, and BIOVIA Discovery Studio Visualizer 2024 was used to evaluate structural and physicochemical changes. Results: The analysis of 81 RGL3 variants identified 5 likely benign and 76 variants of uncertain significance (VUS), all of which were missense mutations. Structural modeling using AlphaFold 2 revealed three key domains: RasGEF_NTER, RasGEF, and RA, where mutations induced conformational changes. Ramachandran plot validation confirmed 79.7% of residues in favored regions, indicating an overall reliable structure. Moreover, mutations within RasGEF and RA domains altered polarity, charge, and stability, suggesting potential functional disruptions. These findings provide insight into the structural consequences of RGL3 mutations, contributing to further functional assessments. Discussion & Conclusion: The identified RGL3 mutations induced physicochemical alterations in key domains, affecting charge, polarity, hydrophobicity, and flexibility. These changes likely disrupt interactions with Ras-like GTPases, impairing GDP-GTP exchange and cellular signaling. Structural analysis highlighted mutations in RasGEF and RA domains that may interfere with activation states, potentially affecting protein function and stability. These findings suggest that mutations in RGL3 could have functional consequences, emphasizing the need for further molecular and functional studies to explore their pathogenic potential.