Banana Blossom Chips is a healthy snack rich in dietary fiber, antioxidants, and plant-based protein. It is a result of combining local Thai ingredients: banana blossoms, which are high in dietary fiber and antioxidants, chickpea flour, a source of plant-based protein, and red jasmine brown rice, which has a low GI value and high antioxidants. It is processed to create crispiness and a unique shape, reduces fat, is gluten-free, and helps maintain nutritional value. Therefore, it is a new alternative for health-conscious consumers and adds value to Thai agricultural products.
เป็นผลงานการพัฒนาผลิตภัณฑ์ของนักศึกษาคณะอุตสาหกรรมอาหาร ที่ได้รับรางวัลรองชนะเลิศอันดับ 2 ในการประกวดนวัตกรรมผลิตภัณฑ์อาหารและเครื่องดื่ม Conovative Award 2024 ครั้งที่ 4 โดย บริษัท ไทยโคโคนัท จำกัด (มหาชน)
คณะเทคโนโลยีการเกษตร
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คณะอุตสาหกรรมอาหาร
Tepache is a traditional Mexican fermented beverage commonly made using pineapple peels, which naturally contain sugars and the enzyme bromelain. These components contribute to its distinctive aroma and unique flavor. This project aims to develop a health-enhancing tepache by fermenting pineapple peels with probiotic yeast and lactic acid bacteria. Additionally, prebiotics, including inulin and xylo-oligosaccharides, are incorporated as nutrients to support probiotic growth. The resulting synbiotic tepache promotes gut microbiota balance, exhibits antioxidant properties, and enhances the immune system, making it a functional and beneficial beverage for consumers.
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.