The Mahachanok mango sauce is crafted from low-grade mangoes sourced from Ban Nong Bua Chum in Kalasin Province. Utilizing advanced food science technology, it effectively reduces agricultural waste and enhances product quality. This sauce is enriched with prebiotic fiber that supports the growth of beneficial gut microorganisms. With low sugar content, it is a healthy choice free from artificial colors and flavors. Its rich, natural taste makes it versatile, perfect for enhancing a wide variety of dishes, both savory and sweet.
ผลิตภัณฑ์ซอสมะม่วงมหาชนกพัฒนามาจากมะม่วงที่ตกเกรดจากบ้านหนองบัวชุม อำเภอหนองกุงศรี จังหวัดกาฬสินธุ์ เป็นการนำวิทยาศาสตร์การอาหารมาประยุกต์ใช้ให้เกิดประโยชน์สูงสุดต่อการลดของเสียทางการเกษตรและการใช้ทรัพยากรอย่างมีประสิทธิภาพ ซอสมะม่วงนี้มีการเสริมด้วยใยอาหารประเภทพรีไบโอติก ซึ่งช่วยกระตุ้นการเจริญเติบโตของจุลินทรีย์ที่ดีต่อลำไส้ สูตรซอสยังมีปริมาณน้ำตาลต่ำ อีกทั้งไม่มีการแต่งสีและกลิ่น ซึ่งช่วยรักษาคุณภาพและรสธรรมชาติของมะม่วง ทำให้ผลิตภัณฑ์นี้มีความเข้มข้นของรสชาติมะม่วงมหาชนกอย่างแท้จริงและดีต่อสุขภาพ
คณะทันตแพทยศาสตร์
Objective or Background: Dental caries is still one of the most significant dental problems worldwide, with prevalence rates up to 90% among children and adults. Cariogenic bacteria, especially Streptococcus mutans, is the primary microorganism involved in the pathogenesis through carbohydrate metabolism and biofilm formation, which are challenging to eradicate. Histatin-5 (HST-5), a human salivary antimicrobial peptide, has demonstrated antimicrobial activity against various fungal and bacterial pathogens. Phytosphingosine (PHS), an endogenous bioactive sphingolipid found in fungi, plants, and humans, also shows antimicrobial properties. This study aimed to evaluate the killing activity of HST-5 alone and in combination with PHS against S. mutans under biofilm-stimulating conditions. Materials and Methods: Antimicrobial activity against a planktonic culture of S. mutans was evaluated using a time-kill assay, and biofilm-forming capacity was confirmed by crystal violet staining assay. The killing ability against 24h pre-formed biofilm was determined using Transferable Solid Phase (TSP) pin lid model. Synergistic activity between HST-5 and PHS was evaluated using the checkerboard technique. Additionally, the cytotoxicity of the tested agent on human gingival fibroblast cells (hGFs) was assessed after 1 h of incubation using an MTT assay. Results: A time-kill assay revealed that both HST-5 and PHS exhibit time- and concentration-dependent activity against the planktonic form of S. mutans. PHS achieved over 90% killing activity within 15 min at 5 μg/ml, whereas HST-5 required 30 min to reach 90% killing at 20 μM. The biofilm formation capacity of S. mutans was confirmed. The inhibitory concentrations (IC50) of HST-5 and PHS against S. mutans biofilm were 25 μM and 13.5 μg/ml, respectively. A synergistic interaction between HST-5 and PHS, with IC50 values reduced by 8-fold and 16-fold, respectively. No cytotoxic effects were observed in hGFs cells at the concentration of the synergistic interaction. Conclusions: Therefore, the combination of HST-5 and PHS may enhance the effectiveness of anti-infective agents against S. mutans biofilm, potentially preventing the development of dental caries.
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
This work got the idea of bringing the car culture of Thai teenagers to present in a new way through our perspective. Create characters and bring various elements within the culture to combine with what we like. Whether it's stickers, posters and band shirts with acrylic paint techniques.
คณะเทคโนโลยีการเกษตร
This study examines the effects of chemical mutagens, ethyl methane sulfonate (EMS) and colchicine in inducing mutations in Chrysanthemum spp. through tissue culture techniques. In vitro cultures of Chrysanthemum were treated with various concentrations of EMS and colchicine to assess their impact on shoot regeneration and mutation frequency. Results indicated that EMS significantly increased phenotypic variability, leading to enhanced flower color and size, while colchicine treatment effectively induced polyploidy, resulting in plants with greater flower size and overall vigor. Morphological assessments, along with genetic analyses using molecular markers, confirmed the mutations associated with these treatments. The integration of chemical mutagenesis with tissue culture presents a promising approach for developing novel Chrysanthemum varieties with improved ornamental traits.