The growing interest in antioxidant-rich foods is driven by their potential to reduce the risk of chronic diseases such as cancer, cardiovascular conditions, and cellular degeneration. Ginger (Zingiber officinale), banana inflorescence (Musa paradisiaca L.), and roselle (Hibiscus sabdariffa L.) are herbal plants known for their high phenolic content, a crucial component in antioxidant activity. However, the bioactive compounds in these plants are often unstable when exposed to light, temperature, and oxygen, leading to a reduction in their efficacy. This study aims to investigate the optimal ratio of ginger, banana inflorescence, and roselle for encapsulation in liposomes—a technique designed to enhance the stability of bioactive compounds and improve their delivery efficacy. The research evaluates the antioxidant activity of the extracts using DPPH, ABTS, and FRAP methods, alongside total phenolic content (TPC) measurement. The most effective ratio for antioxidant activity will be selected for liposomal encapsulation, employing phospholipids as key structural components. The encapsulation efficiency (EE%) will be calculated to assess the effectiveness of the liposomal delivery system. The findings are expected to identify the optimal combination of ginger, banana inflorescence, and roselle that maximizes antioxidant potency and enhances the stability of bioactive compounds through liposomal encapsulation. This approach offers a promising strategy for developing herbal health supplements that maintain their biological properties over time.
การเสื่อมสภาพของเซลล์จากอนุมูลอิสระเป็นสาเหตุหลักที่นำไปสู่การเกิดโรคเรื้อรังต่าง ๆ เช่น โรคมะเร็ง โรคหัวใจ และการเสื่อมสภาพของเซลล์ในระบบต่าง ๆ ของร่างกาย ดังนั้นการใช้สารต้านอนุมูลอิสระจากธรรมชาติจึงเป็นวิธีหนึ่งในการลดความเสี่ยงจากการเกิดโรคเหล่านี้ ขิง ปลีกล้วย และกระเจี๊ยบ เป็นพืชที่มีสารต้านอนุมูลอิสระและสารฟีนอลิกที่มีคุณสมบัติในการป้องกันความเสื่อมของเซลล์ อย่างไรก็ตาม สารเหล่านี้อาจสูญเสียประสิทธิภาพเมื่อสัมผัสกับปัจจัยภายนอก เช่น แสง ความร้อน และออกซิเจน ดังนั้นการใช้เทคนิคการห่อหุ้มสารด้วยวิธีลิโพโซม จึงช่วยเพิ่มความเสถียรของสารสำคัญและเพิ่มประสิทธิภาพในการนำส่งสารไปยังจุดเป้าหมายจึงเป็นสิ่งสำคัญ
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
The concept of building a friendly city for older people by adjusting the physical environment is considered one of the crucial components of promoting older people’s better health and quality of life. Based on this tenet, designing a suitable footpath and considering older people’s needs are vital to the reduction of risks and the increase of safety in travelling, especially for older people living in Wat-Thad and Wat-Klang communities where the proportion of the elderly has continuously, increased. The research aimed to 1) survey the physical environment of footpath, approaching public assistance, 2) observe the elderly’s behavior and satisfaction on footpath in communities, and 3) create the proposal concept in developing the suitable footpath with the elderly’s need in city area. This research used various tools, including the questionnaire on the footpath’s physical environment to analyse problems, limitations, and footpath potentials, the interview of staff in the Engineering Division, Khon Kaen municipality and the questionnaires collecting travelling behaviour, satisfaction and attitude of elderly on the footpath in community. The data analysis the physical environment following six components in the monitoring list showed three used descriptive statistics. Interestingly, from 370 samples, the results of investigating qualified evaluations, namely 1) land utilisation in the communities, 2) linking the transportation network, and 3) beautifully attractive places for walking. However, three unqualified evaluations were 1) safety footpath availability, 2) design for all people, and 3) walking on the footpath to access public assistance and facilities. Moreover, the results from the questionnaire to study older people’s travelling behaviour, indicated that the most travelling objectives were grocery shopping and accessing the recreation sites with frequent visits three to five times per week. Furthermore, older people’s satisfaction with the community footpath was overall at a high level, This research proposed suggestions for developing a safe footpath to ensure safe walking access to facilities and public assistance.
คณะวิศวกรรมศาสตร์
This research suggested natural hemp fiber-reinforced ropes (FRR) polymer usage to reinforce recycled aggregate square concrete columns that contain fired-clay solid brick aggregates in order to reduce the high costs associated with synthetic fiber-reinforced polymers (FRPs). A total of 24 square columns of concrete were fabricated to conduct this study. The samples were tested under a monotonic axial compression load. The variables of interest were the strength of unconfined concrete and the number of FRRlayers. According to the results, the strengthened specimens demonstrated an increased compressive strength and ductility. Notably, the specimens with the smallest unconfined strength demonstrated the largest improvement in compressive strength and ductility. Particularly, the compressive strength and strain were enhanced by up to 181% and 564%, respectively. In order to predict the ultimate confined compressive stress and strain, this study investigated a number of analytical stress–strain models. A comparison of experimental and theoretical findings deduced that only a limited number of strength models resulted in close predictions, whereas an even larger scatter was observed for strain prediction. Machine learning was employed by using neural networks to predict the compressive strength. A dataset comprising 142 specimens strengthened with hemp FRP was extracted from the literature. The neural network was trained on the extracted dataset, and its performance was evaluated for the experimental results of this study, which demonstrated a close agreement.
คณะศิลปศาสตร์
**Innovative Walking Stick "Buddy Take Care"** The "Buddy Take Care" walking stick is designed to physically support the elderly or individuals recovering from injuries, enabling convenient mobility, reducing the risk of falls, and enhancing walking safety. It is crafted as a keychain-style walking stick with a one-touch open-close mechanism. Building upon existing market products, the Buddy walking stick incorporates additional functionalities such as a portable flashlight, a medicine compartment, and an AirTag slot to maximize utility. Its design prioritizes ease of use, convenience, and safety, specifically tailored for elderly users