KMITL Innovation Expo 2025 Logo

Investigation of the Optimal Ratio of Ginger, Banana Flower, and Roselle in Liposomal Encapsulation to Enhance Antioxidant Activity and Total Phenolic Content

Abstract

The growing interest in antioxidant-rich foods is driven by their potential to reduce the risk of chronic diseases such as cancer, cardiovascular conditions, and cellular degeneration. Ginger (Zingiber officinale), banana inflorescence (Musa paradisiaca L.), and roselle (Hibiscus sabdariffa L.) are herbal plants known for their high phenolic content, a crucial component in antioxidant activity. However, the bioactive compounds in these plants are often unstable when exposed to light, temperature, and oxygen, leading to a reduction in their efficacy. This study aims to investigate the optimal ratio of ginger, banana inflorescence, and roselle for encapsulation in liposomes—a technique designed to enhance the stability of bioactive compounds and improve their delivery efficacy. The research evaluates the antioxidant activity of the extracts using DPPH, ABTS, and FRAP methods, alongside total phenolic content (TPC) measurement. The most effective ratio for antioxidant activity will be selected for liposomal encapsulation, employing phospholipids as key structural components. The encapsulation efficiency (EE%) will be calculated to assess the effectiveness of the liposomal delivery system. The findings are expected to identify the optimal combination of ginger, banana inflorescence, and roselle that maximizes antioxidant potency and enhances the stability of bioactive compounds through liposomal encapsulation. This approach offers a promising strategy for developing herbal health supplements that maintain their biological properties over time.

Objective

การเสื่อมสภาพของเซลล์จากอนุมูลอิสระเป็นสาเหตุหลักที่นำไปสู่การเกิดโรคเรื้อรังต่าง ๆ เช่น โรคมะเร็ง โรคหัวใจ และการเสื่อมสภาพของเซลล์ในระบบต่าง ๆ ของร่างกาย ดังนั้นการใช้สารต้านอนุมูลอิสระจากธรรมชาติจึงเป็นวิธีหนึ่งในการลดความเสี่ยงจากการเกิดโรคเหล่านี้ ขิง ปลีกล้วย และกระเจี๊ยบ เป็นพืชที่มีสารต้านอนุมูลอิสระและสารฟีนอลิกที่มีคุณสมบัติในการป้องกันความเสื่อมของเซลล์ อย่างไรก็ตาม สารเหล่านี้อาจสูญเสียประสิทธิภาพเมื่อสัมผัสกับปัจจัยภายนอก เช่น แสง ความร้อน และออกซิเจน ดังนั้นการใช้เทคนิคการห่อหุ้มสารด้วยวิธีลิโพโซม จึงช่วยเพิ่มความเสถียรของสารสำคัญและเพิ่มประสิทธิภาพในการนำส่งสารไปยังจุดเป้าหมายจึงเป็นสิ่งสำคัญ

Other Innovations

Architectural design of a floating resort for divers

คณะสถาปัตยกรรม ศิลปะและการออกแบบ

Architectural design of a floating resort for divers

Koh Tao, a picturesque island in Thailand, is famous for its breathtaking coral reefs and vibrant marine life, attracting diving enthusiasts from all over the world. Despite its natural beauty, the island currently lacks innovative accommodations that enhance the visitor experience and promote environmental sustainability. This project proposes the development of a unique four-star floating resort with underwater villas, designed to offer an extraordinary lodging experience that fosters a deeper connection with the marine environment. By incorporating sustainable practices into the resort's design and operations, the project addresses the growing demand for eco-friendly tourism in the region. The floating resort concept aims not only to provide guests with an immersive experience but also to raise awareness about marine conservation. Through eco-friendly design and operations, the resort seeks to set a benchmark for sustainable tourism in Koh Tao, showcasing how accommodations can align with environmental stewardship, benefiting both the local ecosystem and tourism.

Read more
Study of using ceramic tile powder instead of cement

คณะวิศวกรรมศาสตร์

Study of using ceramic tile powder instead of cement

This study focuses on the use of ceramic tile powder as a cement replacement material in concrete at an appropriate ratio. The objective is to investigate the properties of replacing cement with tile powder and to determine the optimal mixing ratio of tile powder in cement mortar that can yield properties equivalent to or superior to conventional cement mortar. The experiment involved preparing cement mortar samples by replacing cement with two types of ceramic tile powder waste from tile manufacturing plants: waste tile powder and rectified tile powder. The mixing process was divided into two parts: Part 1 used a cement and tile powder ratio, while Part 2 used the results of the strength analysis from Part 1 to adjust the ratio accordingly. Various properties were tested, including specific gravity, normal consistency, setting time, tensile strength, and compressive strength. The results of the study revealed that replacing of cement with rectified tile powder provided the highest tensile and compressive strength, comparable to that of conventional cement mortar. Therefore, the use of ceramic tile powder as a replacement can enhance compressive strength while reducing cement usage, which has positive environmental implications by decreasing greenhouse gas emissions from cement production. Furthermore, this approach promotes the effective use of waste materials from the ceramic industry, contributing to the sustainability of the construction industry.

Read more
BAM property Design Contest #9

คณะสถาปัตยกรรม ศิลปะและการออกแบบ

BAM property Design Contest #9

A commercial architecture consists of a community mall and home offices. The project’s main concept concerns the lack of activities around the given site. The project tackles the main issues of underdevelopment by aiming to bring back the liveliness of the local people back by integrating work-life symbolism and natural spaces, resulting in an interesting design.

Read more