This research focuses on the fabrication of graphene oxide (GO) composite membranes using the Phase-Inversion Method, which transforms polymers from liquid to solid through phase separation. This process creates a porous membrane structure, making it highly adaptable, cost-effective, and suitable for wastewater treatment, separation processes, and industrial filtration applications. Graphene oxide, with its nano-layered structure, offers excellent molecular sieving properties, high water permeability, and chemical and mechanical stability, making it an ideal additive for membrane fabrication. The GO-based membrane demonstrates efficient removal of nanoparticles, heavy metal ions (Pb²⁺, Cr⁶⁺, Hg²⁺), organic pollutants, and microorganisms while exhibiting antifouling properties and high hydrophilicity due to oxygen-functional groups. Applications of this membrane include industrial wastewater treatment, desalination, and the removal of pharmaceutical contaminants, such as antibiotics and hormones. The incorporation of GO enhances membrane performance, providing a sustainable and energy-efficient solution for water purification.
ปัญหามลพิษทางน้ำจากโลหะหนัก สารอินทรีย์ และจุลินทรีย์ในน้ำเสียอุตสาหกรรมและน้ำธรรมชาติกำลังเป็นปัญหาระดับโลก เทคโนโลยีเมมเบรน ได้รับความสนใจเนื่องจากมีประสิทธิภาพสูงในการกรองและบำบัดน้ำ กราฟีนออกไซด์ (GO) เป็นวัสดุที่มีโครงสร้างระดับนาโนและคุณสมบัติพิเศษ เช่น การซึมผ่านน้ำสูง ความทนทานทางเคมี และการคัดแยกสารปนเปื้อนอย่างมีประสิทธิภาพ ดังนั้น การพัฒนาเมมเบรนกราฟีนออกไซด์ผ่านกระบวนการ Phase-Inversion Method จึงเป็นแนวทางสำคัญในการสร้าง เมมเบรนคุณภาพสูง ราคาประหยัด และเหมาะสำหรับการใช้งานด้านสิ่งแวดล้อม
คณะวิทยาศาสตร์
Clean Fuel Vehicle Performance Test Service Unit provides performance and efficiency testing services for electric vehicles and vehicles using petroleum fuels, including being a prototype for research projects on clean fuel energy that is environmentally friendly. The main testing tools are the Chassis Dynamometer and the Engine Combustion Exhaust Analyzer. The service unit provides measurement and testing services in accordance with the announcement of the Department of Land Transport on determining the power of electric motors used to drive vehicles according to the Motor Vehicle Act B.E. 2563 for all types of electric vehicles, such as modified electric motorcycles, modified electric tuk-tuks, and modified electric cars, etc.
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
With the current cost of living situation in Thailand continuously rising, many recent graduates face challenges in managing their expenses in alignment with the increasing living costs. Food expenses, even for common street food, continue to surge with no sign of decreasing, despite improvements in raw material costs. Pay-Attention is a website platform designed to help recent graduates gain insights into managing and optimizing their food expenses effectively. It provides guidance on how to spend wisely, ensuring cost-effectiveness while maintaining adequate daily nutritional intake, without falling into monotonous eating habits.
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.