Mangosteen peel (Garcinia mangostana Linn.) extract using hot water (MPE) has been shown to have antibacterial potential in freshwater sea bass (Lates calcarifer) larvae infected with Aeromonas hydrophila. In vitro studies showed that MPE has a minimum inhibitory concentration (MIC) of 25 ppm and a minimum bactericidal concentration (MBC) of 25 ppm. In vivo, sea bass larvae were immersed in various concentrations of MPE at 0 ppm (control), 20 ppm, 40 ppm and 60 ppm, respectively, for 7 days with A. hydrophila. The results showed that the MPE-treated group had a higher survival rate compared to the control group. Hematological parameters showed that the MPE-treated group had significantly increased red blood cell (RBC), white blood cell (WBC) and hemoglobin (Hb) concentrations compared to the control group. In addition, the water quality parameters were not significantly different, except for ammonia concentration, with MPE having an ammonia concentration of 60 ppm being the lowest. All results can indicate that MPE can improve the antibacterial potential and the culture potential of sea bass larvae.
ปลากะพงขาว (Lates calcarifer) เป็นปลาที่ได้รับความนิยมมากที่สุดในอุตสาหกรรมการเพาะเลี้ยงสัตว์น้ำของไทย โดยเลี้ยงในน้ำจืดและน้ำกร่อย คิดเป็น 95.97% ของพื้นที่เพาะเลี้ยงปลาทะเลทั้งหมด ความสามารถในการปรับตัวและความง่ายในการเลี้ยงในน้ำจืดทำให้ตอบสนองความต้องการได้สูง แต่ยังประสบปัญหาโรคที่เกิดจากแบคทีเรีย เช่น Aeromonas hydrophila ซึ่งก่อให้เกิดโรคร้ายแรงและต้องการวิธีป้องกันที่เป็นมิตรต่อสิ่งแวดล้อม เปลือกมังคุด (Garcinia mangostana Linn.) ที่อุดมไปด้วยสารออกฤทธิ์ทางชีวภาพ แสดงคุณสมบัติต้านแบคทีเรียและเสริมภูมิคุ้มกันในสัตว์น้ำ จากการศึกษาพบว่าเปลือกมังคุดมีประสิทธิภาพในการต้านเชื้อโรคในปลา เช่น Vibrio harveyii และ A. hydrophila ซึ่งเป็นทางเลือกที่ยั่งยืนในการจัดการโรคในฟาร์มปลากะพงขาว
คณะอุตสาหกรรมอาหาร
This research aims to develop plant-based Thai traditional sausage(Sai oua) using young jackfruit as the main raw material. To be an alternative to replace meat by studying the development of formula, changes in physical and physical chemistry during the preservation of the product, young jackfruit has dominant properties of meat-like fibres and can absorb the smell and taste of spices well. The results of the study found that young jackfruit that have been boiled at 100 degrees Celsius for 30 minutes have the fibre closest to cooked chicken. In addition, the study of changes during storage at different temperatures found that the colour and Water Activity (Aw) have changed slightly. While the pH value (pH) decreased and the value of Thiobarbituric Acid Reactive Substances (T-BARS) increased. In terms of texture, it was found that the toughness increased and the elasticity decreased. Compared to the control formula, this study suggests that young jackfruit is a suitable raw material for the production of fillings from plants.
คณะทันตแพทยศาสตร์
Aggregatibacter actinomycetemcomitans is a key pathogen in periodontal disease, damaging periodontal ligaments and alveolar bone through biofilm formation. D-LL-31, an engineered antimicrobial peptide, exhibits superior biofilm-killing ability compared to conventional treatments, while DNase I enhances its efficacy by disrupting the biofilm matrix. This study evaluated the combined effects of D-LL-31 and DNase I on A. actinomycetemcomitans biofilms. Results showed that D-LL-31 effectively eradicated biofilms, and its combination with DNase I further enhanced biofilm disruption without cytotoxicity to gingival epithelial cells. The D-LL-31 and DNase I combination shows potential for development as a mouthwash to improve oral health and combat periodontal disease.
คณะวิศวกรรมศาสตร์
This project aims to develop a conceptual prototype of a weapon aiming system that simulates an anti-aircraft gun. Utilizing an optical camera, the system detects moving objects and calculates their trajectories in real time. The results are then used to control a motorized laser pointer with two degrees of freedom (DoF) of rotation, enabling it to aim at the predicted position of the target. Our system is built on the Raspberry Pi platform, employing machine vision software. The object motion tracking functionality was developed using the OpenCV library, based on color detection algorithms. Experimental results indicate that the system successfully detects the movement of a tennis ball at a rate of 30 frames per second (fps). The current phase involves designing and integratively testing the mechanical system for precise laser pointer position control. This project exemplifies the integration of knowledge in electronics (computer programming) and mechanical engineering (motor control).