

Innovation Owner
Miss AMORNRAPEE THIANSRI
Student
Details
Oral disintegrating films (ODFs) dissolve instantly in the mouth, aiding those with dysphagia by using Capsicum Oleoresin to stimulate saliva. This study investigates how sorbitol concentration affects the film's physical and mechanical properties to improve flexibility.
Oral disintegrating films (ODFs) can dissolve in the mouth instantly upon contact with saliva, without the need for water. This study aimed to investigate the effect of sorbitol concentration on the properties of oral disintegrating films containing Capsicum Oleoresin extract, which has properties that stimulate saliva secretion, making swallowing easier. The film was developed to address difficulties in swallowing, especially for individuals with dysphagia.
The films were prepared using different concentrations of sorbitol and tested for:
- Rheological and mechanical properties
- Moisture and free water content
- Thickness and disintegration time
- Contact angle, color, and antioxidant activity
The results indicated that sorbitol played a key role in increasing the flexibility and reducing the brittleness of the films. Additionally, an optimal concentration of sorbitol helped maintain the stability of the Capsicum extract and enhanced its efficacy in stimulating saliva secretion, thereby making swallowing more convenient and reducing oral friction.
Objective
To study the effect of sorbitol on the physicochemical properties of oral disintegrating films.
To study the effect of sorbitol on the physicochemical properties of oral disintegrating films.


