Migraine, a prevalent neurological disorder, is the third most common disease globally, causing significant health and financial burdens. It has four stages: prodrome, aura, headache, and postdrome. The prodrome (also known as premonitory) stage is crucial as it precedes the headache by up to 72 hours. Taking medication during the premonitory peroid has shown to prevent the headache phase . However, the symptoms of premonitory period lack specificity, making it difficult for patients to know if they’re experiencing premonitory symptoms. Calcitonin-gene related peptide (cGRP),is a protein that plays a key role in migraine pathogenesis and studies found that salivary cGRP levels increase during the premonitory stage. This study aims to develop and evaluate a lateral flow immunoassay kit for detecting salivary cGRP levels in migraine patients during the prodrome stage. It can serve as a confirmation tool for premonitory symptoms.
This study has the potential to greatly improve the management and prevention of migraine. The early detection and management could potentially reduce the frequency and severity of migraines, thereby improving the quality of life for patients and reducing their overall burden. Moreover, the confirmatory test for premonitory symptoms provided by this study could help reduce medication overuse, resulting in cost savings for patients, minimizing potential side effects, and potentially lowers the incidence of medication-overuse headaches. Additionally, by providing patients with a predictive tool, the study promotes patient-centered care and encourages patients to take an active role in managing their migraines. The study may also increase awareness and education surrounding premonitory symptoms. Furthermore, if successful, this study could open up for more new, non-invasive, reliable, and accessible approaches to migraine management and prevention.
วิทยาเขตชุมพรเขตรอุดมศักดิ์
This project aims to design and develop a propulsion system for agricultural equipment using RFID technology and evaluate its movement performance on different surfaces, including concrete and grass. The experiment focuses on examining the tag detection range under transmission power levels of 20 dBm, 23 dBm, and 26 dBm, as well as the impact of antenna angles on detection efficiency. Additionally, the system was tested in three movement scenarios: straight path, left turn, and right turn, at distances of 2 meters, 4 meters, and 6 meters. The results indicate that the system achieved the highest average speed of 0.4736 m/s and an average turning angle of 91.6° when moving in a straight path on a concrete surface at a distance of 4 meters. On a grass surface at the same distance, the average speed was 0.4483 m/s, with an average turning angle of 91.1°. For left and right turns, the movement on the concrete surface generally exhibited a higher average speed than on grass, particularly at a distance of 4 meters, where differences in turning angles were observed. This study provides insights into the factors affecting the movement of agricultural mowing equipment and serves as a foundation for enhancing the efficiency of propulsion systems in future developments.
คณะเทคโนโลยีสารสนเทศ
The AfterDay Horizon project is a two-player survival game developed to raise awareness of the impact of climate change. It leverages Virtual Reality (VR) technology and a website as gaming platforms. In the game, players experience a world where civilization has collapsed due to global warming, forcing the remaining population to live in bunkers to avoid environmental dangers. AfterDay Horizon focuses on collaboration between the two players to complete various missions that help the bunker’s inhabitants survive as long as possible. These missions are designed to encourage teamwork and decision-making in challenging scenarios, while also raising awareness of the potential consequences of climate change if left unresolved. Preliminary testing of the game showed that players successfully completed the missions and worked well together. However, some missions were complex and time-consuming, indicating areas for improvement to enhance the overall enjoyment and gameplay experience.
คณะเทคโนโลยีการเกษตร
Supplementing broilers with different levels of fructooligosaccharides (FOS) under stress conditions, such as higher stocking densities and recycled litter that were not a significant difference in broiler performance, carcass quality and meat quality between the FOS-supplemented groups and the control group (p>0.05). FOS supplementation improved intestinal health by increasing the villus height to crypt depth ratio Lactobacillus populations increased, and Escherichia coli decreased with FOS supplementation. The heterophil-to-lymphocyte ratio was reduced which indicated lower stress.