Migraine, a prevalent neurological disorder, is the third most common disease globally, causing significant health and financial burdens. It has four stages: prodrome, aura, headache, and postdrome. The prodrome (also known as premonitory) stage is crucial as it precedes the headache by up to 72 hours. Taking medication during the premonitory peroid has shown to prevent the headache phase . However, the symptoms of premonitory period lack specificity, making it difficult for patients to know if they’re experiencing premonitory symptoms. Calcitonin-gene related peptide (cGRP),is a protein that plays a key role in migraine pathogenesis and studies found that salivary cGRP levels increase during the premonitory stage. This study aims to develop and evaluate a lateral flow immunoassay kit for detecting salivary cGRP levels in migraine patients during the prodrome stage. It can serve as a confirmation tool for premonitory symptoms.
This study has the potential to greatly improve the management and prevention of migraine. The early detection and management could potentially reduce the frequency and severity of migraines, thereby improving the quality of life for patients and reducing their overall burden. Moreover, the confirmatory test for premonitory symptoms provided by this study could help reduce medication overuse, resulting in cost savings for patients, minimizing potential side effects, and potentially lowers the incidence of medication-overuse headaches. Additionally, by providing patients with a predictive tool, the study promotes patient-centered care and encourages patients to take an active role in managing their migraines. The study may also increase awareness and education surrounding premonitory symptoms. Furthermore, if successful, this study could open up for more new, non-invasive, reliable, and accessible approaches to migraine management and prevention.
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
This research focuses on the design of a Metaverse Prototype Thai Film Archive (Public Organization) to study immersive experiences. The aims were to: 1) examine design concepts and technologies for digital immersion, 2) create and showcase these designs in the Metaverse cinema, and 3) evaluate the results and formulate knowledge for virtual exhibition design using qualitative research methods, including prototype testing with participant interviews to assess satisfaction. The design principles consisted of architectural, exhibition, and user experience concepts, leading to a virtual world creation process involving 3D structural modeling, interactive functionalities, and exhibition layout before prototype testing. The evaluation included tests by ten participants and group discussions on overall experience, cinema content value, Metaverse design, and educational enhancement in museums. The design evaluation indicated a 70% positive overall experience, with half of the users finding stable usability. However, significant viewing barriers were identified, with a high need for operational instructions and navigational aids. Content understanding and Metaverse interaction were perceived positively, and the educational aspect was highly valued. The study concludes that while the overall experience was good, technology limitations (as of 2023) and interaction challenges require ongoing refinement to improve stability and usability, although the educational value was affirmed as strong.
คณะวิศวกรรมศาสตร์
This study focuses on the use of ceramic tile powder as a cement replacement material in concrete at an appropriate ratio. The objective is to investigate the properties of replacing cement with tile powder and to determine the optimal mixing ratio of tile powder in cement mortar that can yield properties equivalent to or superior to conventional cement mortar. The experiment involved preparing cement mortar samples by replacing cement with two types of ceramic tile powder waste from tile manufacturing plants: waste tile powder and rectified tile powder. The mixing process was divided into two parts: Part 1 used a cement and tile powder ratio, while Part 2 used the results of the strength analysis from Part 1 to adjust the ratio accordingly. Various properties were tested, including specific gravity, normal consistency, setting time, tensile strength, and compressive strength. The results of the study revealed that replacing of cement with rectified tile powder provided the highest tensile and compressive strength, comparable to that of conventional cement mortar. Therefore, the use of ceramic tile powder as a replacement can enhance compressive strength while reducing cement usage, which has positive environmental implications by decreasing greenhouse gas emissions from cement production. Furthermore, this approach promotes the effective use of waste materials from the ceramic industry, contributing to the sustainability of the construction industry.
คณะวิทยาศาสตร์
Eco Grow Pellets are high-porosity plant-growing clay pellets made from ceramic industrial sediment, blended with ground chicken bone to enhance calcium and essential minerals, promoting strong and healthy plant growth. They are suitable for all types of plants, especially those requiring well-aerated soil with good water drainage. Eco Grow Pellets are an innovative clay-based growing medium designed to optimize plant cultivation efficiency. Their high porosity structure allows for excellent air and water circulation, reducing soil compaction and waterlogging—common causes of root rot and stunted growth. Additionally, the pellets are enriched with calcium and essential minerals from ground chicken bones, reinforcing plant structure and enhancing root strength, enabling better nutrient absorption. This product is made from 100% recycled ceramic industrial sediment, aligning with the principles of Zero Waste and the BCG Economy Model. It helps minimize industrial waste while transforming discarded materials into high-value, eco-friendly growing media. Eco Grow Pellets are ideal for vegetables, flowers, and potted plants, offering ease of use, cleanliness, and safety. They contribute to sustainable agriculture by improving both crop productivity and environmental health.