The design site of 22 hectares of agricultural land in this area is located in Tatata District, Iglenburg Province. The design concept of this area aims to encourage farmers and communities to earn income from the agricultural products produced in this area, and emphasizes that this area is a "living market", which can not only create food from a variety of crops, but also establish a balanced ecosystem and promote biodiversity in this area. The market will become a sustainable market area, which is not only beneficial to society in promoting economy, but also beneficial to the environment. The area will serve as a social and learning center, where community members can fully exchange agricultural information and experience and stimulate the economy in the community in another way.
เพื่อศึกษาการออกแบบภูมิทัศน์
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.
คณะอุตสาหกรรมอาหาร
In recent years, many people have shown greater interest in plant-based proteins because of their health benefits and lower impact on the environment. This study will look at the physical and chemical properties of chickpeas and red beans. It will also create a plant-based burger that tastes and feels similar to meat-based burgers while providing comparable nutrition. We will steam the ingredients and then analyze important properties such as texture, color, water activity (aW), pH, and how well they retain water and oil. Additionally, we will conduct a sensory evaluation to understand consumer preferences.
วิทยาลัยนวัตกรรมการผลิตขั้นสูง
The research on improving the strength of solid electrolytes aims to enhance the properties of solid electrolyte materials produced from cement and additives that help develop the cement structure to generate electricity. The main components include sodium chloride (NaCl) and graphite, which contribute to the material’s ability to generate a weak electrical current. The objective is to develop an electricity-generating flooring material. This study involves preparing a mixture of cement, water, sodium chloride (NaCl), and graphite to enhance the material’s electrical conductivity. It is highly anticipated that this research will lead to the development of concrete flooring capable of generating electricity and can be further expanded for future applications.