This study aims to investigate the co-encapsulation technique of vitamin C and coenzyme Q10 within liposomes to enhance their stability and encapsulation efficiency and evaluate their antioxidant activity and release behavior under simulated gastrointestinal conditions. Liposomes were prepared using the High-Speed Homogenization Method, and their characteristics, including particle size, zeta potential, encapsulation efficiency, and antioxidant activity, were analyzed using DPPH, ABTS, and FRAP assays. The results demonstrated that co-encapsulation significantly improved the stability of vitamin C and coenzyme Q10 compared to single encapsulation. The liposomes exhibited high encapsulation efficiency and maintained strong antioxidant activity. The release profile under simulated gastrointestinal conditions also indicated a sustained and controlled release. These findings highlight the potential of the co-encapsulation technique in enhancing the efficacy of functional bioactive compounds, making it applicable to the food and nutraceutical industries.
ประเทศไทยกำลังก้าวเข้าสู่สังคมผู้สูงอายุ ทำให้เกิดความต้องการผลิตภัณฑ์ที่ช่วยเสริมสุขภาพ โดยเฉพาะสารต้านอนุมูลอิสระที่ช่วยป้องกันการเสื่อมของเซลล์ โคเอนไซม์คิวเท็น (CoQ10) เป็นสารสำคัญที่ช่วยผลิตพลังงานในเซลล์และมีบทบาทในการปกป้องเซลล์จากความเสียหาย โดยปกติโคเอนไซม์คิวเท็นเป็นสารที่ร่างกายสามารถผลิตเองได้แต่เมื่ออายุมากขึ้นจะทำให้การผลิตโคเอนไซม์คิวเท็นลดลง ส่วน วิตามินซี เป็นสารต้านอนุมูลอิสระที่ช่วยเสริมภูมิคุ้มกันและกระตุ้นการสร้างคอลลาเจน การห่อหุ้มร่วม (Co-encapsulation) ใน ลิโปโซม (Liposome) ช่วยเพิ่มเสถียรภาพของสารสำคัญ ป้องกันการเสื่อมสลายของสารสำคัญในระบบทางเดินอาหาร โดยลิโปโซมสามารถกักเก็บสารที่ละลายในน้ำและไขมันไว้ภายในโครงสร้างเดียวกัน นอกจากนี้ จากการศึกษายังพบว่าการใช้เทคนิคนี้สามารถเพิ่มประสิทธิภาพในการเก็บรักษาได้ ดังนั้น การวิจัยนี้จึงมีเป้าหมายเพื่อพัฒนาการห่อหุ้มร่วมของวิตามินซีและโคเอนไซม์คิวเท็น เพื่อเพิ่มประสิทธิภาพของสารทั้งสองในการดูแลสุขภาพและความงาม
คณะเทคโนโลยีการเกษตร
This project presents a design and management approach for agricultural land in Kanchanaburi Province. The case study area is situated in Wangdong Subdistrict, Mueang Kanchanaburi District, covering an area of approximately 18 rai (7.2 acres). As the user seeks a simplified lifestyle in the countryside, surrounded by nature, the design aligns with this vision of simplicity and sustainability. The land is systematically allocated to optimize the benefits for both daily living and agricultural industry development. The crop cultivation zones are designed to suit the local climate and plant varieties, ensuring high-quality yields for continuous utilization. Meanwhile, the livestock zones are clearly delineated to maintain balance and organization. This approach not only ensures food security and income generation but also promotes a lifestyle that harmonizes with nature, minimizes environmental impact, and supports the long-term development of an efficient and eco-friendly agricultural industry. Comprehensive attention is given to the positioning of various zones, considering wind direction and sunlight exposure. Additionally, the design undergoes a rigorous drafting and review process to ensure the optimal outcomes for the land's utilization.
คณะเทคโนโลยีการเกษตร
During this cooperative education program at the Bang Bo District Agricultural Office, Samut Prakan Province, a study was conducted on the costs and returns of rice cultivation using chemical inputs compared to using biopesticides in combination with chemical inputs among farmers in Bang Phli Noi Subdistrict, Bang Bo District, Samut Prakan Province.The objectives of this study were: To examine the costs and returns of rice cultivation using chemical inputs compared to using biopesticides in combination with chemical inputs among farmers in Bang Phli Noi Subdistrict, Bang Bo District, Samut Prakan Province. To explore the challenges of using biopesticides in rice cultivation among farmers in Bang Phli Noi Subdistrict, Bang Bo District, Samut Prakan Province. The study found that in the 2024/25 growing season, the total production cost for rice cultivation using biopesticides in combination with chemical inputs was 5,099.50 THB per rai, consisting of variable costs of 4,432.50 THB per rai and fixed costs of 667.00 THB per rai. Meanwhile, the total production cost for rice cultivation using only chemical inputs was 5,129.00 THB per rai, consisting of variable costs of 4,390.00 THB per rai and fixed costs of 739.00 THB per rai. The cost difference between the two methods was 114.50 THB per rai. Regarding the returns on rice cultivation in the 2024/25 growing season, the field using biopesticides in combination with chemical inputs yielded 1,000.00 kilograms per rai, with an average selling price of 8,500.00 THB per rai. Farmers earned a total revenue of 8,585.00 THB per rai and a profit of 3,485.50 THB per rai. On the other hand, the field using only chemical inputs yielded 1,000.00 kilograms per rai, with an average selling price of 8,500.00 THB per rai. Farmers earned a total revenue of 8,500.00 THB per rai and a profit of 3,371.00 THB per rai. The total income difference between the two cultivation methods was 114.50 THB per rai. In terms of challenges related to the procurement of biopesticides, it was found that biopesticides are difficult to obtain, with limited or no availability in certain areas. Additionally, relevant agencies do not provide continuous support for biopesticides, making this the most significant issue. Regarding the use of biopesticides, the most critical challenge is that once fresh biopesticides are mixed, they must be used immediately and cannot be stored, as their effectiveness deteriorates over time.
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
When it comes to the general perception of death, it is often seen as something negative or inauspicious. However, the end or death of someone can sometimes be the beginning of change, influencing thoughts, lifestyles, and attitudes in a positive way for those around them. For students aged 13-18, accessing and understanding this topic remains a challenge. Most available information is often presented in complex forms that are difficult for young people to grasp. Moreover, teaching materials in schools often lack creativity and engagement, leading to a decline in students’ interest in this subject. To address this issue, a website has been designed as an accessible and creative resource. It aims to deepen young people's understanding of the impact of actions and the death of individuals on the world they live in, while inspiring them to become part of creating positive change for the future.