This study aims to investigate the co-encapsulation technique of vitamin C and coenzyme Q10 within liposomes to enhance their stability and encapsulation efficiency and evaluate their antioxidant activity and release behavior under simulated gastrointestinal conditions. Liposomes were prepared using the High-Speed Homogenization Method, and their characteristics, including particle size, zeta potential, encapsulation efficiency, and antioxidant activity, were analyzed using DPPH, ABTS, and FRAP assays. The results demonstrated that co-encapsulation significantly improved the stability of vitamin C and coenzyme Q10 compared to single encapsulation. The liposomes exhibited high encapsulation efficiency and maintained strong antioxidant activity. The release profile under simulated gastrointestinal conditions also indicated a sustained and controlled release. These findings highlight the potential of the co-encapsulation technique in enhancing the efficacy of functional bioactive compounds, making it applicable to the food and nutraceutical industries.
ประเทศไทยกำลังก้าวเข้าสู่สังคมผู้สูงอายุ ทำให้เกิดความต้องการผลิตภัณฑ์ที่ช่วยเสริมสุขภาพ โดยเฉพาะสารต้านอนุมูลอิสระที่ช่วยป้องกันการเสื่อมของเซลล์ โคเอนไซม์คิวเท็น (CoQ10) เป็นสารสำคัญที่ช่วยผลิตพลังงานในเซลล์และมีบทบาทในการปกป้องเซลล์จากความเสียหาย โดยปกติโคเอนไซม์คิวเท็นเป็นสารที่ร่างกายสามารถผลิตเองได้แต่เมื่ออายุมากขึ้นจะทำให้การผลิตโคเอนไซม์คิวเท็นลดลง ส่วน วิตามินซี เป็นสารต้านอนุมูลอิสระที่ช่วยเสริมภูมิคุ้มกันและกระตุ้นการสร้างคอลลาเจน การห่อหุ้มร่วม (Co-encapsulation) ใน ลิโปโซม (Liposome) ช่วยเพิ่มเสถียรภาพของสารสำคัญ ป้องกันการเสื่อมสลายของสารสำคัญในระบบทางเดินอาหาร โดยลิโปโซมสามารถกักเก็บสารที่ละลายในน้ำและไขมันไว้ภายในโครงสร้างเดียวกัน นอกจากนี้ จากการศึกษายังพบว่าการใช้เทคนิคนี้สามารถเพิ่มประสิทธิภาพในการเก็บรักษาได้ ดังนั้น การวิจัยนี้จึงมีเป้าหมายเพื่อพัฒนาการห่อหุ้มร่วมของวิตามินซีและโคเอนไซม์คิวเท็น เพื่อเพิ่มประสิทธิภาพของสารทั้งสองในการดูแลสุขภาพและความงาม
คณะเทคโนโลยีการเกษตร
This research aimed to (1) analyze the problems and needs in designing labels for catfish strip products of the Lam Sai Phatthana Community Enterprise Group, (2) develop the labels for catfish strip products, and (3) evaluate the satisfaction levels of consumers and community group members with the developed labels. The study involved 17 members of the community enterprise group and 151 consumers. Research methods included in-depth interviews and questionnaires to gather satisfaction data. The results showed that the newly developed product labels were effective in attracting attention and building trust in the product. The satisfaction levels among the Lam Sai Phatthana Community Enterprise Group members and consumers were high (x ̅= 4.17 and 3.75, respectively).
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
In the world of blood donation, there are 2 types of people: those who donate blood and those who don't. Most campaigners emphasize how to persuade more people to donate blood and recruit more new blood donors. We believe that even though such focus is important, there're more critical aspects that might have been neglected, which is: for those who have already made up their minds to be blood doners, will they be successful in donating when the time comes? According to our studies, only 63 % of attempted doners are successful. Regrettably, 37 % has to go home disappointed as their bodies are not fit for the conditions required by Red Cross medical staff at blood donation centers (which include some most basic preparations such as low-fat food intake and 8-hours sleep on the night before). Our campaign, ‘Blood in Need, Buddy Indeed’, focuses on 2 aspects. Firstly, to persuade more people to donate blood. Secondly, for those who have made up their minds to donate blood, we will provide necessary support (both body and mind) so that they are fully prepared and successful in donating blood when the time comes via networks of systems, staffs and the newly designed and prototype of the application ‘Blood D’. Our campaign covers the whole ‘before/during/after’ experience of users (as blood doners). Support includes assessment of their current condition whether they are within the requirement of Red Cross Blood Bank. ‘Blood D’ will also provide relevant information on blood donating events, such as locations, and time booking. Once sign-up, the application “Blood D” will sent friendly reminder and clear infographic on how to prepare their bodies as daily notifications during the 7 days countdown. This is to ensure that the users’ blood will be ‘D’ (homophone of the Thai word ‘ดี’ which mean ‘good’ and at the same time playing on the word ‘ Buddy’) or be the ‘good blood’ that can save lives for those in need. After organizing 4 blood donation events both within and outside the KMITL. The numbers of successful blood doners have increased from 63 % to 78 % (this number is the average of 4 events, with the most successful event of 89%). The campaign has won the first runner up in national blood donation campaign competition. It is highly anticipated that once the application “Blood D” is fully launched, it will help increase the amount of blood collected up to 15% with the same numbers of existing doners.
คณะเทคโนโลยีการเกษตร
The objective of this experiment was to determine the effect of nitrogen and potassium concentration combination with photoperiod on the growth of Viola in a plant factory to increase the quality of the products, reduce the production time and increase the production cycle throughout the year. The experimental plan was 3x3 Factorial in CRD with nine treatments and three replications (six plants per replication). The factor of this study was two factors; the first factor was three different concentrations of nitrogen and potassium in ratios of 1:1, 1:2 and 2:1. The second factor was the application of different photoperiods. There were 1) 24-hours photoperiod, 2) 8-hours light/16-hours dark photoperiod (Induced flowering state: 13-hours light/11-hours dark photoperiod) and 3) 5-hours light/3-hours dark photoperiod. Controlled temperature at 25 °C, the EC=1.5-2.0 mS/cm and the pH=5.8-6.5 in all treatment. The result showed that the concentration of N: K in the ratio of 1:1 combined with 24-hour photoperiod was the most vegetative growth and also maximizes reproductive growth. The overall great sensory evaluation was an acceptable level and suitable for cooking or decorating dishes. Therefore, the concentration of N: K in the ratio of 1:1 combined with 24-hour photoperiod is the best treatment to increase the quality of the product, reduce the production time of viola flowers in each cycle from 90-100 days down to 43-45 days which is good for farmers.