Nowadays, assembling a computer is considered something close to many people. Everyone has a chance to catch it. which knowledge of various components of computers and skills in assembling computers. These 2 things mentioned above are things that the general public should have basic knowledge and understanding about. For the self-assembly of computers, We therefore would like to provide knowledge to the general public who wants to learn how to assemble a computer, including information about its components. Through presentation in the form of learning media using VR technology, which will help reduce the problem of errors. and resources used in assembly Ready to create excitement for users by simulating computer assembly for users to interact within the virtual world. experience and provide knowledge before actually putting it into practice with real equipment This project was therefore created for those interested in assembling computers. Especially for people who have no experience in computer assembly. Including people who would like to have the opportunity to try building a computer by themselves.
ในการประกอบคอมพิวเตอร์หนึ่งเครื่องนั้นจำเป็นต้องมีอุปกรณ์จริงในการประกอบ หากไม่มีก็ไม่สามารถทำได้ อีกทั้งผู้ที่จะประกอบไม่มีความรู้อาจส่งผลให้ต้องใช้เวลานานในการประกอบ และ ในการปฏิบัติจริงในบางกรณีอาจส่งผลเสียกับอุปกรณ์กรณีที่ประกอบผิดขั้นตอน ซึ่งโครงงานนี้จะช่วยให้ผู้ใช้สามารถได้ทดลองประกอบคอมพิวเตอร์ได้ด้วยตนเอง พร้อมกับให้ความรู้เบื้องต้น โดยผ่านการนำเสนอในรูปแบบสื่อการสอนด้วยเทคโนโลยีความจริงเสมือน เพื่อให้ผู้ใช้ได้มีปฏิสัมพันธ์ และ ได้จำลองสถานการณ์ ซึ่งจะช่วยให้ผู้ใช้งานสามารถเข้าใจ และ ได้ความรู้ในการประกอบคอมพิวเตอร์มากยิ่งขึ้น ก่อนที่จะนำความรู้ที่ได้ไปปฏิบัติกับอุปกรณ์จริงได้อย่างถูกต้อง
คณะวิศวกรรมศาสตร์
Motor control is a critical process for muscle contraction, which is initiated by nerve impulses governed by the motor cortex. This process is vital for performing activities of daily living (ADLs). Consequently, a disruption in communication between the brain and muscles, as seen in various chronic conditions and diseases, can impair bodily movement and ADLs. Evaluating the interaction between brain function and motor control is significant for the diagnosis and treatment of motor control disorders; moreover, it can contribute to the development of brain-computer interfaces (BCIs). The purpose of this study is to investigate brain activation in designed upper extremity motor control tasks in regulating the pushing force in different brain regions; and develop investigation methods to assess motor control tasks and brain activation using a robotic arm to guide upper extremity force and motor control. Eighteen healthy young adults were asked to perform upper extremity motor control tasks and recorded the hemodynamic signals. Functional Near-Infrared Spectroscopy (fNIRs) and robotic arms were used to assess brain activation and the regulation of pushing force and extremity motor control. Two types of motion, static and dynamic, move along a designated trajectory in both forward and backward directions, and three different force levels selected from a range of ADLs, including 4, 12, and 20 N, were used as force-regulating upper extremity motor control tasks. The hemodynamic responses were measured in specific regions of interest, namely the primary motor cortex (M1), premotor cortex (PMC), supplementary motor area (SMA), and prefrontal cortex (PFC). Utilizing a two-way repeated measures ANOVA with Bonferroni correction (p < 0.00625) across all regions, we observed no significant interaction effect between force levels and movement types on oxygenated hemoglobin (HbO) levels. However, in both contralateral (c) and ipsilateral (i) PFC, movement type—static versus dynamic—significantly affected brain activation. Additionally, cM1, iPFC, and PMC showed a significant effect of force level on brain activation.
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.
คณะอุตสาหกรรมอาหาร
Plant-based refers to food or products that are primarily made from plants. It can be divided into two categories: one is food that comes entirely from plants and does not include any animal products, and the other is food that contains small amounts of animal products, such as products that contain milk and eggs in limited quantities, which may also be considered part of the definition of plant-based. Plant-based meat products that closely resemble real meat and attract consumers are considered a relatively new innovation. Although tofu, tempeh, and seitan have been around for a long time, recent discoveries have led to the production of plant-based meat products that provide a sensory experience, making it difficult for consumers to distinguish between real meat and plant-based meat. Furthermore, the development of plant-based food products must prioritize quality and safety to maximize consumer benefits. Textured Vegetable Protein (TVP) is a plant-based protein made from soybeans using an extruder. It is used as a primary ingredient in the production of plant-based food products due to several advantages. These include: • High Protein Content: TVP is made from soybeans with the fat extracted, resulting in a high protein content. • Texture: When rehydrated, TVP has a texture that closely resembles meat. • Versatility: TVP has a neutral flavor, allowing it to easily absorb the flavors of various seasonings and sauces. • Cost-Effectiveness: Compared to other protein sources, TVP is relatively inexpensive while providing desirable characteristics. These benefits make TVP an attractive option in the production of plant-based foods. This study focuses on developing TVP into a plant-based crab cake and investigating the shelf life of the product in a tightly sealed container under refrigeration. It also analyzes the hygiene and cleanliness of the production process and how these factors affect the presence or growth of microorganisms that may pose a risk to consumers, referencing the cold food safety standards of Thailand. Finally, recommendations for cleaning operational areas will be provided to establishments as a guideline for developing preliminary food safety procedures in laboratory settings.