Freshwater scarcity is a global crisis due to limited accessible freshwater resources and rising demand. Seawater desalination is a key solution but is energy-intensive and reliant on fossil fuels, leading to high costs and environmental impacts. This study aims to investigate the use of solar thermal energy from an evacuated tube collector for freshwater production via evaporation and condensation. The focus is on analyzing system efficiency by comparing freshwater yield with energy input. The findings may contribute to the development of sustainable desalination technologies suitable for freshwater-scarce regions.
ปัจจุบันโลกปกคลุมด้วยน้ำถึง 70% ของพื้นที่ทั้งหมด แต่มีทรัพยากรน้ำที่เป็นน้ำจืด (fresh water) ที่สามารถใช้อุปโภค บริโภคได้เพียง 3% ประกอบกับจำนวนประชากรที่เพิ่มสูงขึ้นอย่างต่อเนื่อง จึงเกิดวิกฤตการขาดแคลนน้ำ การแยกเกลือออกจากน้ำทะเลเป็นแนวทางสำคัญในการแก้ไขปัญหานี้ โดยงานวิจัยของเรามุ่งพัฒนาเทคโนโลยีแยกเกลือออกจากน้ำทะเลโดยใช้พลังงานแสงอาทิตย์ ผ่านระบบท่อสุญญากาศ (ETSC) เพื่อลดต้นทุน พึ่งพาพลังงานสะอาด และเพิ่มประสิทธิภาพการผลิตน้ำจืด โดยเฉพาะในพื้นที่แห้งแล้งที่ขาดแคลนน้ำ
คณะวิศวกรรมศาสตร์
Nowadays, consumers may have experienced situations where they don't know which product to use based on their skin problems, the product they use doesn't give the desired results, the product is not worth the price, allergic to certain chemicals in the product ,or use multiple products and have ingredients that should not be used together leading to irritation. For this reason, we develop an application to analyze skin care product ingredients to solve such problems. This allows consumers to correctly understand information about the ingredients in products and know which products they should use according to their skin problems without having to rely on chemical knowledge and get products that are the best value for money. The project has integrated software knowledge to develop an application for analyzing skin care product ingredients. To find and recommend suitable skin care products to consumers. The information on various important ingredients has been collected from reliable articles and research.
คณะวิศวกรรมศาสตร์
The design and development of an electric locomotive for the TRRN Railway Challenge 2025 aims to enhance learning potential and apply various theories in practical settings. The focus is on developing the locomotive to pass various tests, including acceleration, automatic braking system, noise, vibration, energy consumption, and durability throughout the competition. Additionally, the project helps improve skills in writing engineering design reports, which enables students to develop their analytical and discussion abilities in order to successfully complete each test according to the competition rules.
คณะทันตแพทยศาสตร์
Objective or Background: Dental caries is still one of the most significant dental problems worldwide, with prevalence rates up to 90% among children and adults. Cariogenic bacteria, especially Streptococcus mutans, is the primary microorganism involved in the pathogenesis through carbohydrate metabolism and biofilm formation, which are challenging to eradicate. Histatin-5 (HST-5), a human salivary antimicrobial peptide, has demonstrated antimicrobial activity against various fungal and bacterial pathogens. Phytosphingosine (PHS), an endogenous bioactive sphingolipid found in fungi, plants, and humans, also shows antimicrobial properties. This study aimed to evaluate the killing activity of HST-5 alone and in combination with PHS against S. mutans under biofilm-stimulating conditions. Materials and Methods: Antimicrobial activity against a planktonic culture of S. mutans was evaluated using a time-kill assay, and biofilm-forming capacity was confirmed by crystal violet staining assay. The killing ability against 24h pre-formed biofilm was determined using Transferable Solid Phase (TSP) pin lid model. Synergistic activity between HST-5 and PHS was evaluated using the checkerboard technique. Additionally, the cytotoxicity of the tested agent on human gingival fibroblast cells (hGFs) was assessed after 1 h of incubation using an MTT assay. Results: A time-kill assay revealed that both HST-5 and PHS exhibit time- and concentration-dependent activity against the planktonic form of S. mutans. PHS achieved over 90% killing activity within 15 min at 5 μg/ml, whereas HST-5 required 30 min to reach 90% killing at 20 μM. The biofilm formation capacity of S. mutans was confirmed. The inhibitory concentrations (IC50) of HST-5 and PHS against S. mutans biofilm were 25 μM and 13.5 μg/ml, respectively. A synergistic interaction between HST-5 and PHS, with IC50 values reduced by 8-fold and 16-fold, respectively. No cytotoxic effects were observed in hGFs cells at the concentration of the synergistic interaction. Conclusions: Therefore, the combination of HST-5 and PHS may enhance the effectiveness of anti-infective agents against S. mutans biofilm, potentially preventing the development of dental caries.