This research studies the effect of CBD on the excitability of mice nociceptive trigeminal ganglion neurons. The electrophysiological parameters of the mouse trigeminal ganglion cells are measured using a Whole Cell Current Clamp Model on a primary cell culture treated with 0.5 uM CBD for 24 hours compared to a control group. After obtaining the results statistical analysis is done using a Mann Whitney-U test.
ยาที่ใช้ในกาารักษาอาการปวดในปัจจุบัน เช่น NSAIDs และยาโอปิออยด์อาจก่อให้เกิดผลข้างเคียงที่ไม่พึงประสงค์ ทำให้ไม่เหมาะสมสำหรับประชากรบางกลุ่มโดยเฉพาะผู้สูงอายุ ดังนั้นการศึกษานี้จึงทําเพื่อประเมินฤทธิของ CBD ต่อการลดความไวในการรับรู้ความเจ็บปวดเพื่อดูเป็นยาทางเลือกในการรักษาอาการปวดในอนาคต
คณะวิทยาศาสตร์
This special problem aims to study and compare the performance of predicting the air quality index (AQI) using five ensemble machine learning methods: random forest, XGBoost, CatBoost, stacking ensemble of random forest and XGBoost, and stacking ensemble of random forest, SVR, and MLP. The study uses a dataset from the Central Pollution Control Board of India (CPCB), which includes fifteen pollutants and nine meteorological variables collected between January, 2021 and December, 2023. In this study, there were 1,024,920 records. The performance is measured using three methods: root mean square error (RMSE), mean absolute error (MAE), and coefficient of determination. The study found that the random forest and XGBoost stacking ensemble had the best performance measures among the three methods, with the minimum RMSE of 0.1040, the minimum MAE of 0.0675, and the maximum of 0.8128. SHAP-based model interpretation method for five machine learning methods. All methods reached the same conclusion: the two variables that most significantly impacted the global prediction were PM2.5 and PM10, respectively.
คณะอุตสาหกรรมอาหาร
The activities of the project's operations consist of: checking microbe on sample food, hygienic condition of cooker, containers and materials, sanitation knowledge and private sanitation and food quality of canteen and cleaning of cooker. The Food Safety Management program collaborated with the Property Management office, planned the operations, and assessed food vendors based on the SAN 20 food safety standards requirements. Using A.13 testing kits, we conducted testing for coliform bacteria contamination in food, containers, equipment, and hand contact surfaces, collecting 6 samples. These included samples such as prepared food, areas in front of the store, and food handlers' hands. Additionally, we used A.11 testing kits to test for coliform bacteria contamination in water and ice. The analysis of results, including physical, microbiological, and chemical aspects, serve as a guideline for improving the quality and safety of food production and service in the institution's canteen.
วิทยาเขตชุมพรเขตรอุดมศักดิ์
Bone tissue scaffolds are made from biomaterials that support rapid repair and healing. Scaffold fabricators have produced materials that are able to degrade a biosystem or human body excellently. Thus, this work aims to study the optimization of materials, shape, and the 3D printing process with FDM. Finite element analysis is also used to predict mechanical properties of the scaffold and find the optimal shape and pore size. However, the materials studied include PLA, PCL, and HA.