This research studies the effect of CBD on the excitability of mice nociceptive trigeminal ganglion neurons. The electrophysiological parameters of the mouse trigeminal ganglion cells are measured using a Whole Cell Current Clamp Model on a primary cell culture treated with 0.5 uM CBD for 24 hours compared to a control group. After obtaining the results statistical analysis is done using a Mann Whitney-U test.
ยาที่ใช้ในกาารักษาอาการปวดในปัจจุบัน เช่น NSAIDs และยาโอปิออยด์อาจก่อให้เกิดผลข้างเคียงที่ไม่พึงประสงค์ ทำให้ไม่เหมาะสมสำหรับประชากรบางกลุ่มโดยเฉพาะผู้สูงอายุ ดังนั้นการศึกษานี้จึงทําเพื่อประเมินฤทธิของ CBD ต่อการลดความไวในการรับรู้ความเจ็บปวดเพื่อดูเป็นยาทางเลือกในการรักษาอาการปวดในอนาคต
คณะบริหารธุรกิจ
This project is a part of KMITL business student’s thesis. The topic is business plan about blazers and trousers made by recycled fabric
คณะวิศวกรรมศาสตร์
This cooperative education project aims to enhance speed and facilitate the verification process for stock issuance, transfers, distributions, and receipts in the warehouse. The primary focus is to address issues related to wasted time and delays in operational processes. Through analysis, it was found that SAP, the current system, involves complex processes requiring specialized expertise. Although the company has developed the iWarehouse system to improve efficiency, delays and procedural complexity persist. To resolve these challenges, Power BI was utilized to visualize data related to stock issuance, transfers, distributions, and receipts, allowing warehouse staff to work more efficiently by minimizing waste and accelerating processes. Additionally, Power Automate was integrated to automate the processing of received stock numbers from emails, reducing errors and delays caused by manual data entry. The results of this improvement indicate a significant increase in employee efficiency and a noticeable reduction in wasted time. Upon project completion, the findings and development approach will be provided to the company for further enhancement.
คณะวิทยาศาสตร์
Efficient logistics management requires the development of advanced tools to streamline delivery operations. This study aims to optimize vehicle routes for an animal feed store and develop a web-based application for route planning. The research compares two optimization methods: the Branch and Bound Method and Clustering with the Branch and Bound Method. These methods are evaluated against the store’s existing delivery route by analyzing differences in average travel distance across three dependent groups using Repeated Measures ANOVA. The findings reveal a statistically significant difference in average daily travel distances among the three methods at a 0.05 significance level. The Branch and Bound Method yields the shortest average daily travel distance. Additionally, pairwise comparisons of total daily travel distances using the Paired t-test confirm that the Branch and Bound Method produces the most efficient route with statistical significance at 0.05 level. Implementing this method can reduce total travel distance by 957.51, representing a 30.88% reduction, which translates into fuel cost savings of 2,579.45 THB per month. Based on these results, the Branch and Bound Method was selected for implementation in a web-based application. The application features an intuitive user interface, product inventory management, and optimized daily delivery route recommendations for the case study store. Following development, the web application was deployed and tested in real-world operations. The results demonstrate that it effectively provides map-based route recommendations, ensuring ease of use and accessibility on standard mobile devices.