"Niyom Thai" represents health-centric footwear adorned with traditional Thai patterns, embodying an innovative approach to sustainable development tailored to the current needs of local communities. These shoes utilize natural materials to mitigate fatigue and integrate safety technologies, including location tracking via a mobile application and heart rate monitoring. This addresses the aspects of convenience and well-being in both daily life and travel
เนื่องจากปัจจัยผู้คนให้ความสนใจเรื่องสุขภาพมากขึ้นเเละรองเท้านับเป็นอีกหนึ่งเทรนด์สุขภาพที่กำลังได้รับความสนใจในยุคนี้ อีกทั้งผ้าไทยจัดเป็นศิลปะ ที่มีเอกลักษณ์เเละความสวยงาม คณะผู้จัดทำจึงมีเเนวคิดที่จะออกแบบลวดลายไทยให้เข้ากับยุคสมัยเเต่ยังคงความเป็นเป็นไทยและนำเทคโนโลยีมาผสมผสานเข้าด้วยกันให้เกิดนวัตกรรมรองเท้าเพื่อสุขภาพลายไทย
วิทยาเขตชุมพรเขตรอุดมศักดิ์
This research focuses on the design and development of a prototype Artificial Intelligence of Things (AIoT) system for monitoring and controlling irrigation using weather information. The system consists of four main components: 1) Weather Station – This component includes various sensors such as air temperature, relative humidity, wind speed, and sunlight duration, among others, to collect real-time weather data. 2) Controller Unit – This unit is equipped with machine learning algorithms or models to estimate the reference evapotranspiration (ETo) and calculate the plant’s water requirement by integrating the crop coefficient (Kc) with other plant-related data. This enables the system to determine the optimal irrigation amount based on plant needs automatically. 3) User Interface (UI) and Display – This section allows farmers or users to input relevant information, such as plant type, soil type, irrigation system type, number of water emitters, planting distance, and growth stages. It also provides a display for monitoring and interaction with the system. 4) Irrigation Unit – This component is responsible for controlling the water supply and managing the irrigation emitters to ensure efficient water distribution based on the calculated requirements.
คณะศิลปศาสตร์
This innovation reduces costs and enhances queue management efficiency in restaurants, ensuring an organized system, minimizing wait times, and improving customer handling.
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.