Mulberry Kefir is a fermented drink made from ripe mulberry fruit, made from ripe mulberry juice. Its pinkish-red color is the color of the natural anthocyanin in mulberries. Anthocyanins have antioxidant properties and contain the prebiotic fructo-oligosaccharides, the probiotic microorganisms Lactobacillus and Saccharomeces. It has a sweet and sour taste, is fizzy and has a little alcohol. The taste and fizz come from production technology, which uses a fermentation process from microorganisms. Mulberry kefir is considered a functional beverage made from plants (Plant Based Beverage), suitable for people who are lactose intolerant and those who do not consume beverages made from milk. It makes you feel refreshed after drinking it.
ผลหม่อนสุก เป็นผลิตผลจากหม่อนซึ่งมีการไปแปรรูปเป็นแยมหม่อน น้ำหม่อน ไวน์หม่อน การนำผลหม่อนมาแปรรูปเป็นเครื่องดื่มคีเฟอร์ในกลุ่มของ water kefir เป็นแนวคิดที่เพิ่มความหลากหลายให้กับเครื่องดื่มจากผลหม่อนโดยใช้เทคโนโลยีการหมักด้วจุลินทรีย์แลคโทบาซิลลัส และยีสต์ ได้เป็นเครื่องดื่มจากพืชที่มีความโดดเด่นด้านสี รสชาติ
คณะทันตแพทยศาสตร์
Objective or Background: Dental caries is still one of the most significant dental problems worldwide, with prevalence rates up to 90% among children and adults. Cariogenic bacteria, especially Streptococcus mutans, is the primary microorganism involved in the pathogenesis through carbohydrate metabolism and biofilm formation, which are challenging to eradicate. Histatin-5 (HST-5), a human salivary antimicrobial peptide, has demonstrated antimicrobial activity against various fungal and bacterial pathogens. Phytosphingosine (PHS), an endogenous bioactive sphingolipid found in fungi, plants, and humans, also shows antimicrobial properties. This study aimed to evaluate the killing activity of HST-5 alone and in combination with PHS against S. mutans under biofilm-stimulating conditions. Materials and Methods: Antimicrobial activity against a planktonic culture of S. mutans was evaluated using a time-kill assay, and biofilm-forming capacity was confirmed by crystal violet staining assay. The killing ability against 24h pre-formed biofilm was determined using Transferable Solid Phase (TSP) pin lid model. Synergistic activity between HST-5 and PHS was evaluated using the checkerboard technique. Additionally, the cytotoxicity of the tested agent on human gingival fibroblast cells (hGFs) was assessed after 1 h of incubation using an MTT assay. Results: A time-kill assay revealed that both HST-5 and PHS exhibit time- and concentration-dependent activity against the planktonic form of S. mutans. PHS achieved over 90% killing activity within 15 min at 5 μg/ml, whereas HST-5 required 30 min to reach 90% killing at 20 μM. The biofilm formation capacity of S. mutans was confirmed. The inhibitory concentrations (IC50) of HST-5 and PHS against S. mutans biofilm were 25 μM and 13.5 μg/ml, respectively. A synergistic interaction between HST-5 and PHS, with IC50 values reduced by 8-fold and 16-fold, respectively. No cytotoxic effects were observed in hGFs cells at the concentration of the synergistic interaction. Conclusions: Therefore, the combination of HST-5 and PHS may enhance the effectiveness of anti-infective agents against S. mutans biofilm, potentially preventing the development of dental caries.
คณะวิศวกรรมศาสตร์
An automated hydroponic system for household use has been developed to cater to individuals with limited space who wish to conveniently and easily grow their own salad greens at home. This system is designed to automatically control nutrient delivery by setting appropriate electrical conductivity (EC) and pH levels tailored to the specific salad greens being grown. It includes artificial lighting to enable cultivation in confined spaces with insufficient sunlight and is more cost-effective than similar systems available on the market. System testing revealed that the automated control of EC and pH values performed effectively, achieving the preset levels within 30 minutes and maintaining them consistently throughout operation. In an experiment growing green oak lettuce using a simulated balcony setup, the plants demonstrated a higher growth rate compared to conventional methods, particularly when artificial lighting was used.
คณะอุตสาหกรรมอาหาร
This study focused on the development of an edible film containing Terminalia chebula Retz extract for the treatment of oral ulcers. The film was designed to dissolve in the mouth without the need for swallowing or chewing, which is suitable for people with canker sores or oral inflammation. Terminalia chebula extract has been shown to have several pharmacological properties, including antimicrobial, antioxidant, and anti-inflammatory activities.