Microalgae are rich in bioactive compounds that may contribute to the growth of probiotics. This study aims to evaluate the effectiveness of crude extracts from intracellular components of the microalga Chlorella sp. KLSc61 in promoting the growth of the probiotic bacterium Lactiplantibacillus plantarum JCM1149 under simulated gastrointestinal conditions.

• Methodology: Intracellular extracts were obtained using 70% (v/v) ethanol.
• Testing: The effects on probiotic growth were tested at concentrations of 0.1%, 0.75%, and 1.5% using the drop plate method.

The findings will provide insights into the potential of Chlorella sp. KLSc61 extracts in enhancing probiotic growth, which could lead to the development of synbiotic dietary supplements. Additionally, this study may serve as a foundation for further research on the role of microalgal extracts in gut health and immune system modulation.