The research on improving the strength of solid electrolytes aims to enhance the properties of solid electrolyte materials produced from cement and additives that help develop the cement structure to generate electricity. The main components include sodium chloride (NaCl) and graphite, which contribute to the material’s ability to generate a weak electrical current. The objective is to develop an electricity-generating flooring material. This study involves preparing a mixture of cement, water, sodium chloride (NaCl), and graphite to enhance the material’s electrical conductivity. It is highly anticipated that this research will lead to the development of concrete flooring capable of generating electricity and can be further expanded for future applications.
ในปัจจุบัน ความต้องการใช้พลังงานไฟฟ้าเพิ่มขึ้นนอย่างต่อเนื่อง ส่งผลให้เกิดการพัฒนาเทคโนโลยีและนวัตกรรมใหม่ ๆ เพื่อเพิ่มแหล่งพลังงานทางเลือกที่มีความยั่งยืนและเป็นมิตรต่อสิ่งแวดล้อม หนึ่งในแนวทางที่ได้รับความสนใจ คือการพัฒนาวัสดุที่สามารถผลิตและกักเก็บพลังงานไฟฟ้าได้ในตัวเอง ซึ่งสามารถนำไปใช้ในโครงสร้างพื้นฐานต่าง ๆเช่น พื้นทางเดิน อาคาร หรือพื้นที่สาธารณะ ดังนั้น งานวิจัยนี้จึงมีเป้าหมายเพื่อพัฒนาและปรับปรุงคุณสมบัติของเซลล์อิเล็กโทรไลต์ชนิดแข็งที่มีโครงสร้างพื้นฐานจากซีเมนต์ โดยมุ่งเน้นการเพิ่มความแข็งแรงของวัสดุควบคู่ไปกับการรักษาคุณสมบัติการนำไฟฟ้า เพื่อให้สามารถนำไปใช้งานเป็นวัสดุปูพื้นที่สามารถผลิตกระแสไฟฟ้าได้ งานวิจัยนี้คาดหวังว่าจะเป็นแนวทางสำคัญในการ พัฒนาวัสดุก่อสร้างสามารถต่อยอดไปสู่การประยุกต์ใช้ในอนาคตได้อย่างมีประสิทธิภาพ
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
The thesis artwork titled “The Red Mist” presents a narrative adapted from a short story of the same name by Assistant Professor Chatnarong Wisutkul in 2003. The story is set in a future world where people's greed and selfishness have led to a war, forcing them to rely on "breathing machines" to survive in the "red toxic mist." Phakin, a 15-year-old boy, embarks on a journey with a group of refugees. As they pass through abandoned cities, they encounter a boy without a breathing machine who has recently lost his father. Phakin decides to help him, despite objections from others. The boy tries to end his life by shutting off his breathing machine, and when Phakin intervenes to save him, he collapses from inhaling the toxic air. Witnessing Phakin's selfless act, the others are moved and join forces to save both of them. Phakin demonstrates that in difficult times, humans must cooperate and help each other rather than being divided and selfish.
คณะบริหารธุรกิจ
This book introduces basic management concepts that are applicable to technological innovation development. It encompasses various tech settings like Agro & Health tech, in addition to the more commonly referred digital sector.
คณะแพทยศาสตร์
Background: The RGL3 gene plays a role in key signal transduction pathways and has been implicated in hypertension risk through the identification of a copy number variant deletion in exon 6. Genome-wide association studies have highlighted RGL3 as associated with hypertension, providing insights into the genetic underpinnings of the condition and its protective effects on cardiovascular health. Despite these findings, there is a lack of data that confirms the precise role of RGL3 in hypertension. Additionally, the functional impact of certain variants, particularly those classified as variants of uncertain significance, remains poorly understood. Objectives: This study aims to analyze alterations in the RGL3 protein structure caused by mutations and validate the location of the ligand binding sites. Methods: Clinical variants of the RGL3 gene were obtained from NCBI ClinVar. Variants of uncertain significance and likely benign were analyzed. Multiple sequence alignment was conducted using BioEdit v7.7.1. AlphaFold 2 predicted the wild-type and mutant 3D structures, followed by quality assessment via PROCHECK. Functional domain analysis of RasGEF, RASGEF_NTER, and RA domains was performed, and BIOVIA Discovery Studio Visualizer 2024 was used to evaluate structural and physicochemical changes. Results: The analysis of 81 RGL3 variants identified 5 likely benign and 76 variants of uncertain significance (VUS), all of which were missense mutations. Structural modeling using AlphaFold 2 revealed three key domains: RasGEF_NTER, RasGEF, and RA, where mutations induced conformational changes. Ramachandran plot validation confirmed 79.7% of residues in favored regions, indicating an overall reliable structure. Moreover, mutations within RasGEF and RA domains altered polarity, charge, and stability, suggesting potential functional disruptions. These findings provide insight into the structural consequences of RGL3 mutations, contributing to further functional assessments. Discussion & Conclusion: The identified RGL3 mutations induced physicochemical alterations in key domains, affecting charge, polarity, hydrophobicity, and flexibility. These changes likely disrupt interactions with Ras-like GTPases, impairing GDP-GTP exchange and cellular signaling. Structural analysis highlighted mutations in RasGEF and RA domains that may interfere with activation states, potentially affecting protein function and stability. These findings suggest that mutations in RGL3 could have functional consequences, emphasizing the need for further molecular and functional studies to explore their pathogenic potential.