The research on improving the strength of solid electrolytes aims to enhance the properties of solid electrolyte materials produced from cement and additives that help develop the cement structure to generate electricity. The main components include sodium chloride (NaCl) and graphite, which contribute to the material’s ability to generate a weak electrical current. The objective is to develop an electricity-generating flooring material. This study involves preparing a mixture of cement, water, sodium chloride (NaCl), and graphite to enhance the material’s electrical conductivity. It is highly anticipated that this research will lead to the development of concrete flooring capable of generating electricity and can be further expanded for future applications.
ในปัจจุบัน ความต้องการใช้พลังงานไฟฟ้าเพิ่มขึ้นนอย่างต่อเนื่อง ส่งผลให้เกิดการพัฒนาเทคโนโลยีและนวัตกรรมใหม่ ๆ เพื่อเพิ่มแหล่งพลังงานทางเลือกที่มีความยั่งยืนและเป็นมิตรต่อสิ่งแวดล้อม หนึ่งในแนวทางที่ได้รับความสนใจ คือการพัฒนาวัสดุที่สามารถผลิตและกักเก็บพลังงานไฟฟ้าได้ในตัวเอง ซึ่งสามารถนำไปใช้ในโครงสร้างพื้นฐานต่าง ๆเช่น พื้นทางเดิน อาคาร หรือพื้นที่สาธารณะ ดังนั้น งานวิจัยนี้จึงมีเป้าหมายเพื่อพัฒนาและปรับปรุงคุณสมบัติของเซลล์อิเล็กโทรไลต์ชนิดแข็งที่มีโครงสร้างพื้นฐานจากซีเมนต์ โดยมุ่งเน้นการเพิ่มความแข็งแรงของวัสดุควบคู่ไปกับการรักษาคุณสมบัติการนำไฟฟ้า เพื่อให้สามารถนำไปใช้งานเป็นวัสดุปูพื้นที่สามารถผลิตกระแสไฟฟ้าได้ งานวิจัยนี้คาดหวังว่าจะเป็นแนวทางสำคัญในการ พัฒนาวัสดุก่อสร้างสามารถต่อยอดไปสู่การประยุกต์ใช้ในอนาคตได้อย่างมีประสิทธิภาพ
คณะวิทยาศาสตร์
This work presents the fabrication of the handheld meter for potentiometric detection of Hg (II). The meter was constructed based on using an ion-sensitive field-effect transistor (ISFET) platform. The developed meter provides high accuracy and precision (%Recovery was in the range of 92.55 - 109.32 and %RSD was 2.38). It was applied to the analysis of cosmetic samples. The results by the developed electrode were not significantly different at a 95% confidence level compared to the results by using ICP-OES.
คณะแพทยศาสตร์
Background: The RGL3 gene plays a role in key signal transduction pathways and has been implicated in hypertension risk through the identification of a copy number variant deletion in exon 6. Genome-wide association studies have highlighted RGL3 as associated with hypertension, providing insights into the genetic underpinnings of the condition and its protective effects on cardiovascular health. Despite these findings, there is a lack of data that confirms the precise role of RGL3 in hypertension. Additionally, the functional impact of certain variants, particularly those classified as variants of uncertain significance, remains poorly understood. Objectives: This study aims to analyze alterations in the RGL3 protein structure caused by mutations and validate the location of the ligand binding sites. Methods: Clinical variants of the RGL3 gene were obtained from NCBI ClinVar. Variants of uncertain significance and likely benign were analyzed. Multiple sequence alignment was conducted using BioEdit v7.7.1. AlphaFold 2 predicted the wild-type and mutant 3D structures, followed by quality assessment via PROCHECK. Functional domain analysis of RasGEF, RASGEF_NTER, and RA domains was performed, and BIOVIA Discovery Studio Visualizer 2024 was used to evaluate structural and physicochemical changes. Results: The analysis of 81 RGL3 variants identified 5 likely benign and 76 variants of uncertain significance (VUS), all of which were missense mutations. Structural modeling using AlphaFold 2 revealed three key domains: RasGEF_NTER, RasGEF, and RA, where mutations induced conformational changes. Ramachandran plot validation confirmed 79.7% of residues in favored regions, indicating an overall reliable structure. Moreover, mutations within RasGEF and RA domains altered polarity, charge, and stability, suggesting potential functional disruptions. These findings provide insight into the structural consequences of RGL3 mutations, contributing to further functional assessments. Discussion & Conclusion: The identified RGL3 mutations induced physicochemical alterations in key domains, affecting charge, polarity, hydrophobicity, and flexibility. These changes likely disrupt interactions with Ras-like GTPases, impairing GDP-GTP exchange and cellular signaling. Structural analysis highlighted mutations in RasGEF and RA domains that may interfere with activation states, potentially affecting protein function and stability. These findings suggest that mutations in RGL3 could have functional consequences, emphasizing the need for further molecular and functional studies to explore their pathogenic potential.
คณะอุตสาหกรรมอาหาร
The reuse of cooking oil in food preparation leads to oil degradation and the formation of harmful compounds due to oxidation. This study focuses on enhancing the stability of used palm oil through ultrasound-assisted infusion with three varieties of banana blossoms: Kluai Khai, Kluai Hom, and Kluai Nam Wa, which are rich in phenolic compounds and antioxidants. The research investigates the restoration of used palm oil by infusing dried and powdered banana blossoms using ultrasonic treatment at different temperatures and durations. The quality of the infused oil was evaluated through physical (water activity, moisture content, and color), chemical (peroxide value, acid value, and Thio barbituric acid reactive substances), and antioxidant activity (DPPH, ABTS, and FRAP) analyses.