The research on improving the strength of solid electrolytes aims to enhance the properties of solid electrolyte materials produced from cement and additives that help develop the cement structure to generate electricity. The main components include sodium chloride (NaCl) and graphite, which contribute to the material’s ability to generate a weak electrical current. The objective is to develop an electricity-generating flooring material. This study involves preparing a mixture of cement, water, sodium chloride (NaCl), and graphite to enhance the material’s electrical conductivity. It is highly anticipated that this research will lead to the development of concrete flooring capable of generating electricity and can be further expanded for future applications.
ในปัจจุบัน ความต้องการใช้พลังงานไฟฟ้าเพิ่มขึ้นนอย่างต่อเนื่อง ส่งผลให้เกิดการพัฒนาเทคโนโลยีและนวัตกรรมใหม่ ๆ เพื่อเพิ่มแหล่งพลังงานทางเลือกที่มีความยั่งยืนและเป็นมิตรต่อสิ่งแวดล้อม หนึ่งในแนวทางที่ได้รับความสนใจ คือการพัฒนาวัสดุที่สามารถผลิตและกักเก็บพลังงานไฟฟ้าได้ในตัวเอง ซึ่งสามารถนำไปใช้ในโครงสร้างพื้นฐานต่าง ๆเช่น พื้นทางเดิน อาคาร หรือพื้นที่สาธารณะ ดังนั้น งานวิจัยนี้จึงมีเป้าหมายเพื่อพัฒนาและปรับปรุงคุณสมบัติของเซลล์อิเล็กโทรไลต์ชนิดแข็งที่มีโครงสร้างพื้นฐานจากซีเมนต์ โดยมุ่งเน้นการเพิ่มความแข็งแรงของวัสดุควบคู่ไปกับการรักษาคุณสมบัติการนำไฟฟ้า เพื่อให้สามารถนำไปใช้งานเป็นวัสดุปูพื้นที่สามารถผลิตกระแสไฟฟ้าได้ งานวิจัยนี้คาดหวังว่าจะเป็นแนวทางสำคัญในการ พัฒนาวัสดุก่อสร้างสามารถต่อยอดไปสู่การประยุกต์ใช้ในอนาคตได้อย่างมีประสิทธิภาพ
คณะทันตแพทยศาสตร์
Objective or Background: Dental caries is still one of the most significant dental problems worldwide, with prevalence rates up to 90% among children and adults. Cariogenic bacteria, especially Streptococcus mutans, is the primary microorganism involved in the pathogenesis through carbohydrate metabolism and biofilm formation, which are challenging to eradicate. Histatin-5 (HST-5), a human salivary antimicrobial peptide, has demonstrated antimicrobial activity against various fungal and bacterial pathogens. Phytosphingosine (PHS), an endogenous bioactive sphingolipid found in fungi, plants, and humans, also shows antimicrobial properties. This study aimed to evaluate the killing activity of HST-5 alone and in combination with PHS against S. mutans under biofilm-stimulating conditions. Materials and Methods: Antimicrobial activity against a planktonic culture of S. mutans was evaluated using a time-kill assay, and biofilm-forming capacity was confirmed by crystal violet staining assay. The killing ability against 24h pre-formed biofilm was determined using Transferable Solid Phase (TSP) pin lid model. Synergistic activity between HST-5 and PHS was evaluated using the checkerboard technique. Additionally, the cytotoxicity of the tested agent on human gingival fibroblast cells (hGFs) was assessed after 1 h of incubation using an MTT assay. Results: A time-kill assay revealed that both HST-5 and PHS exhibit time- and concentration-dependent activity against the planktonic form of S. mutans. PHS achieved over 90% killing activity within 15 min at 5 μg/ml, whereas HST-5 required 30 min to reach 90% killing at 20 μM. The biofilm formation capacity of S. mutans was confirmed. The inhibitory concentrations (IC50) of HST-5 and PHS against S. mutans biofilm were 25 μM and 13.5 μg/ml, respectively. A synergistic interaction between HST-5 and PHS, with IC50 values reduced by 8-fold and 16-fold, respectively. No cytotoxic effects were observed in hGFs cells at the concentration of the synergistic interaction. Conclusions: Therefore, the combination of HST-5 and PHS may enhance the effectiveness of anti-infective agents against S. mutans biofilm, potentially preventing the development of dental caries.
คณะวิทยาศาสตร์
Developing a Smart Farming Simulation Utilizing LoRa Communication and Presenting Knowledge on LoRa Communication System Components
คณะครุศาสตร์อุตสาหกรรมและเทคโนโลยี
Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang has a vision for sustainable excellence. The mission is to develop learners to be ready for the digital world, develop educational innovations using research as a base, strategic management with good governance, and academic services that benefit society. In this activity, the group of students joined with the Embassy of the Russian Federation in the Kingdom of Thailand, the working group of the Thai Silk and Culture Promotion Association, and the working group of the National Research Office (NRCT) to integrate knowledge to design a silk outfit that combines Thai and Russian cultures, create a network of cooperation in arts, culture, technology, innovation, and dissemination of knowledge and the beauty of Thai silk. The objective is to develop the potential of teachers and students in creative design, listen to the work guidelines from the working group of the Thai Silk and Culture Promotion Association, the working group of the National Research Office (NRCT) via an online meeting. The team of teachers and students from King Mongkut's Institute of Technology Ladkrabang under the name of the "Love Silk" group designed a Thai silk outfit that combines cultures with the identity of Thai silk and studying traditions and cultures of the Russian Federation's clothing. They studied related literature and research documents and integrated knowledge into the design process, inspired by the concept of the Rajapataen outfit. Since the reign of King Chulalongkorn (Rama V) in 1872, together with the clothing culture of the Russian Federation, emphasizing Thai silk, this concept has gone through the process of creating and selecting the design concept (Concept Generation and Selection). The concept received from the embassy was first submitted for feedback on July 25, 2024. There was a suggestion to add more uniqueness to Thai silk through a fashion show presentation by the wife and grandson of the Ambassador of the Russian Federation. Therefore, the designed outfits are 1 set of women's clothes and 1 set of boys' clothes. The women's set has an inner shirt adapted from the royal outfit using silk fabric, Kon Ka-ed pattern, with two separate pieces: 1 shirt and 1 skirt. The jacket is a modified long suit style, plain silk, dark pink and red. The boys' set has a long-sleeved shirt adapted from the contemporary royal style, tailored with cream silk, long slacks tailored with raw betel silk, and a collarless coat with blue silk and lotus pattern. Adapted from the Rajapattan suit with a long collar in an international style. On August 2, 2024, the designed suit and the prototype of the raw fabric suit were brought to the ambassador's wife and nephew to try on. On August 30, 2024, the ambassador was met for the 4th time to bring the silk suit that was cut into a real silk suit. The shirt was given to the ambassador's wife and nephew to try on. It was worn to join the fashion show in the 13th "Thai Silk to the World" Silk Festival at the Naval Auditorium, where lecturers and students from the Faculty of Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang, joined the fashion show in the finale round, which proceeded smoothly. After the event, the working group of the Thai Silk and Culture Promotion Association brought the clothes designed and tailored by the "Rak Prae Mai" team to exhibit Thai Silk to the World Exhibition from September 1-8, 2024 at the Emsphere Shopping Mall. The team summarized the report and compiled a complete report. In the implementation of this project, the Faculty of Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang has received support and facilitation throughout the project. The budget support from the National Research Council of Thailand (NRCT), the support of fabrics for sewing from the Thai Silk and Culture Promotion Association, and the information for designing valuable silk dresses from the Embassy of the Russian Federation in the Kingdom of Thailand are very important factors that made this operation a success. It is a very important experience for the team of teachers and students of Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang. We sincerely hope to receive good cooperation in the future.