The Herby gel are products developed to relieve stress and headaches, which often result from heavy work, a fast-paced lifestyle, or hot and humid weather. The patches are made from natural ingredients such as peppermint, neem leaves, gotu kola, aloe vera, and other herbs that effectively alleviate these symptoms. Free from alcohol, this product is safe to use and provides a cooling, soothing, and refreshing effect on the skin. It is easy to use, convenient to carry, and suitable for use in any situation, making it a practical solution for everyday discomfort.
ที่มา จากการศึกษาคุณสมบัติของสมุนไพรไทยที่มีประโยชน์ในการบรรเทาอาการต่างๆ โดยเฉพาะในเรื่องของการลดความร้อนและการบรรเทาอาการปวดหัว สมุนไพรบางชนิด เช่น ตะไคร้, มะกรูด, และใบสะระแหน่ มีคุณสมบัติในการเย็นและลดอาการปวดได้ดี ซึ่งได้ถูกนำมาใช้ในการพัฒนาเป็นผลิตภัณฑ์ที่สะดวกและใช้งานง่ายในรูปแบบของแผ่นเจลแปะหน้าผาก ที่สามารถแปะบนหน้าผากเพื่อช่วยลดอาการไม่สบายต่างๆ ได้อย่างรวดเร็วและปลอดภัย ความสำคัญ การตอบโจทย์ความต้องการของผู้บริโภคในยุคปัจจุบันที่ต้องการความสะดวกสบายและปลอดภัยในการบรรเทาอาการต่างๆ โดยไม่ต้องพึ่งพายาหรือวิธีการรักษาที่ซับซ้อน แผ่นเจลแปะหน้าผากที่ใช้สมุนไพรจากธรรมชาติช่วยให้ผู้ใช้สามารถบรรเทาอาการปวดหัวหรือไข้ได้อย่างรวดเร็วและมีประสิทธิภาพ อีกทั้งยังลดความเสี่ยงจากผลข้างเคียงที่อาจเกิดจากการใช้สารเคมีหรือยาที่มีสารเสพติด
คณะทันตแพทยศาสตร์
Objective or Background: Dental caries is still one of the most significant dental problems worldwide, with prevalence rates up to 90% among children and adults. Cariogenic bacteria, especially Streptococcus mutans, is the primary microorganism involved in the pathogenesis through carbohydrate metabolism and biofilm formation, which are challenging to eradicate. Histatin-5 (HST-5), a human salivary antimicrobial peptide, has demonstrated antimicrobial activity against various fungal and bacterial pathogens. Phytosphingosine (PHS), an endogenous bioactive sphingolipid found in fungi, plants, and humans, also shows antimicrobial properties. This study aimed to evaluate the killing activity of HST-5 alone and in combination with PHS against S. mutans under biofilm-stimulating conditions. Materials and Methods: Antimicrobial activity against a planktonic culture of S. mutans was evaluated using a time-kill assay, and biofilm-forming capacity was confirmed by crystal violet staining assay. The killing ability against 24h pre-formed biofilm was determined using Transferable Solid Phase (TSP) pin lid model. Synergistic activity between HST-5 and PHS was evaluated using the checkerboard technique. Additionally, the cytotoxicity of the tested agent on human gingival fibroblast cells (hGFs) was assessed after 1 h of incubation using an MTT assay. Results: A time-kill assay revealed that both HST-5 and PHS exhibit time- and concentration-dependent activity against the planktonic form of S. mutans. PHS achieved over 90% killing activity within 15 min at 5 μg/ml, whereas HST-5 required 30 min to reach 90% killing at 20 μM. The biofilm formation capacity of S. mutans was confirmed. The inhibitory concentrations (IC50) of HST-5 and PHS against S. mutans biofilm were 25 μM and 13.5 μg/ml, respectively. A synergistic interaction between HST-5 and PHS, with IC50 values reduced by 8-fold and 16-fold, respectively. No cytotoxic effects were observed in hGFs cells at the concentration of the synergistic interaction. Conclusions: Therefore, the combination of HST-5 and PHS may enhance the effectiveness of anti-infective agents against S. mutans biofilm, potentially preventing the development of dental caries.
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
The forest firefighting suit consists of the following components and uses: The forest firefighting suit is designed and developed to be suitable for the behavior of the officers and the conditions of the work area, consisting of a shirt and pants. The material used in the sewing of the suit is aramid fabric, which has the property of being able to prevent the spread of fire, to prevent the officers from burning while performing their duties in the event that the forest fire spreads close to them, which is different from the current suits that cannot prevent fires. The shirt is designed with a mesh on the side of the body to release internal heat so that air can circulate well. The sleeves at the elbows have a support point to prevent contact with the ground or obstacles. The collar has a slot for a portable fan and a fan air circulation channel on the back, which can be turned on while performing forest firefighting duties, helping to prevent the body temperature from getting too hot, reducing the risk of heatstroke. When the fan battery runs out, it can be removed for charging and put back in when needed. The pants are designed with mesh on the inside or in blind spots to release internal heat so that air can circulate well. The pants at the knees have a support point to prevent contact with the ground or obstacles. The forest firefighting suit, consisting of a shirt and pants, has been designed and developed to be able to be produced domestically, reducing imports from abroad
คณะวิทยาศาสตร์
The synthesis using electrons as reagents instead of oxidants is a method for synthesizing drug molecules in a way that reduces the use of chemicals, thereby minimizing environmental pollution.