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คณะทันตแพทยศาสตร์
Aggregatibacter actinomycetemcomitans is a key pathogen in periodontal disease, damaging periodontal ligaments and alveolar bone through biofilm formation. D-LL-31, an engineered antimicrobial peptide, exhibits superior biofilm-killing ability compared to conventional treatments, while DNase I enhances its efficacy by disrupting the biofilm matrix. This study evaluated the combined effects of D-LL-31 and DNase I on A. actinomycetemcomitans biofilms. Results showed that D-LL-31 effectively eradicated biofilms, and its combination with DNase I further enhanced biofilm disruption without cytotoxicity to gingival epithelial cells. The D-LL-31 and DNase I combination shows potential for development as a mouthwash to improve oral health and combat periodontal disease.
คณะวิศวกรรมศาสตร์
This thesis project was conducted to identify the optimal conditions for producing concentrated butterfly pea juice using vacuum evaporation to preserve key compounds in butterfly pea flowers, such as anthocyanins—natural pigments with high antioxidant properties. The study applies a Box-Behnken Design, a statistical method that facilitates analysis of multiple factors. The research focuses on the ratio of dried butterfly pea flowers to water, extraction temperature, and evaporation temperature, each of which has a direct effect on the preservation of key compounds, color, aroma, and flavor. The results indicate that using a dried flower-to-water ratio of 1:15, an extraction temperature of 60°C, and an evaporation temperature of 40°C under low pressure can minimize the loss of essential compounds and best retain the properties of the concentrated butterfly pea juice. Findings from this research provide a foundation for developing an industrial production process for concentrated butterfly pea juice and enhance the potential for creating new products from butterfly pea flowers.
คณะเทคโนโลยีสารสนเทศ
KinderForest : Puzzle Building Game with VR Technology is designed to utilize Virtual Reality (VR) technology with the primary aim of promoting creative problem-solving skills and basic practical application abilities among players. This project presents the game in an Augmented Virtual Reality (AR VR) format, emphasizing physical engagement of players during gameplay while fostering creativity and fundamental application skills. The project team has chosen to utilize Unreal Engine 5.1 and Oculus Quest 2 virtual reality glasses to develop the game in the form of augmented virtual reality technology. Within the game, there will be various levels that require creative thinking and different approaches to pass. Time constraints will be a crucial element in completing missions and progressing through these levels. Players will physically move their bodies in response to in-game movements. Each level will present unique challenges that will necessitate both physical movement and problem-solving skills. The game will provide different rewards based on the outcomes of mission completion, and players will be informed of their results once they have successfully passed a level.