A conceptual model inspired by Art Deco art, using the luxury, elegance, balance and the use of black and gold, which are the characteristics of Art Deco art, to create a conceptual model that is balanced, stable, elegant, sequential to look dynamic and uses black and gold to express Art Deco luxury.
เพื่อศึกษาเอกลักษณ์และความงามของศิลปะอาร์ตเดโคและนำมาประยุกต์ใช้ในงานออกแบบ
วิทยาลัยวิศวกรรมสังคีต
This project studies how to design a portable, sound-confining space that allows users to practice using their voices without disturbing the surroundings.
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.
คณะวิศวกรรมศาสตร์
This project aims to design and develop an electric tuk-tuk by converting the traditional combustion engine system to an electric system, supporting the reduction of air pollution and promoting sustainable automotive technology. The electric tuk-tuk is designed using a BLDC electric motor and a control system specifically adapted for the unique driving style of three-wheeled vehicles in Thailand. The study considers suitable energy systems and includes interviews with traditional tuk-tuk drivers to ensure the vehicle meets everyday usability needs. The findings suggest that adopting electric tuk-tuks not only reduces emissions and PM2.5 particulate matter but also enhances an eco-friendly image for Thailand’s tourism sector while supporting domestic innovation and economic growth.