This study aims to develop alginate-based hydrogels reinforced with carrageenan and gellan gum as composite materials for oral drug delivery. Alginate, a naturally derived polymer from brown algae, forms a gel upon exposure to cations such as calcium ions, enhancing the hydrogel’s structural integrity. Carrageenan and gellan gum, both polysaccharides, further improve stability and encapsulation efficiency. This research investigates the physical properties, mechanical strength, encapsulation capacity, and swelling behavior of hydrogel beads under simulated gastrointestinal conditions. The findings are expected to demonstrate that incorporating carrageenan and gellan gum enhances the durability and stability of hydrogel beads while enabling controlled release of active compounds in the gastrointestinal tract. These advanced hydrogel beads hold significant potential for applications in the food and pharmaceutical industries as effective oral delivery systems for bioactive substances.
ในงานวิจัยนี้มีจุดมุ่งหมายเพื่อพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัม โดยมีคุณสมบัติที่ช่วยเสริมความแข็งแรงและความยืดหยุ่นให้กับโครงสร้างของไฮโดรเจลบีดส์ เพื่อเพิ่มความทนทานและเสถียรภาพมากขึ้น ซึ่งสามารถนำมาใช้ในการห่อหุ้มและปกป้องสารสำคัญ โดยมุ่งเน้นการควบคุมการปลดปล่อยสารสำคัญไปยังจุดเป้าหมาย การศึกษานี้จะครอบคลุมถึงลักษณะทางกายภาพ ความแข็งแรงของไฮโดรเจลบีดส์ และความสามารถในการกักเก็บสารสำคัญ ลักษณะทางกายภาพและการบวม (Swelling) ภายใต้สภาวะจำลองทางเดินอาหาร โดยใช้สารจำลองน้ำย่อยทั้งในกระเพาะอาหารและลำไส้ การพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัมมีศักยภาพในการนำไปใช้งานในอุตสาหกรรมเภสัชกรรมและอาหารที่ต้องการห่อหุ้มสารสำคัญที่มีประสิทธิภาพสูงในอนาคต
คณะวิศวกรรมศาสตร์
The Diabetes Meal Management Application is a digital health tool designed to empower Type 2 diabetic patients in managing their diet and blood sugar levels more effectively. With features like personalized meal recommendations, nutrient tracking, and seamless integration with wearable blood glucose monitors via Blood sugar measuring device (CGM), the application enables users to monitor glucose fluctuations in real time and adjust dietary choices accordingly. Built with the Flutter framework and supported by a backend of Express.js and MongoDB, the application prioritizes a user-friendly interface, ensuring easy navigation and encouraging consistent engagement with meal planning and health tracking. Preliminary user trials show that the application contributes to more stable blood sugar levels and improved adherence to dietary recommendations, helping users reduce health risks associated with diabetes complications. By offering a proactive approach to diabetes management, the application reduces the need for frequent clinical interventions, thus potentially lowering medical costs over time. This project highlights the promising role of digital health solutions in supporting personalized diabetes care, emphasizing the potential for scalable, user-centered interventions that foster long-term health improvements for diabetic patients.
คณะวิศวกรรมศาสตร์
Nowadays, rail transportation has a significant impact on people's lives and economic growth. Consequently, the number of rail systems being built around our country has dramatically increased. This process causes various types of pollution, such as noise and rail-way vibration, which can badly affect the life of citizens who live nearby. The most popular way to solve this problem recently is to decrease the noise from the sound source or to adjust the vibration by attaching a Track Damper to the railway. This technique is being used in many countries especially in Europe and Australia because it is cheap and has high efficiency. The key piece called Track Dampers are made by AUT company’s Thailand for a period of time. The company produces Track Dampers for the owner of the technology so as to sell more than 300,000 pieces of it overseas. Furthermore, the demand of Track Dampers grows as the railway systems expand. Unfortunately, the imported synthetic materials, which are used to create Track Dampers, are made from environmentally unfriendly sources. As a result, this research aims to develop the product to be environmentally-safe by replacing some imported materials with Thai’s local content; which are natural rubber and rubber crumbs. Furthermore, the product will be added value by mounting with embedded sensors for real-time monitoring of track vibration, noise, and rail temperature. All embedded devices developed will sense, collect, and automatically send to cloud by wireless technology platform. The AI and IOT platform will also be developed for safety, security, and maintenance proposed of railway track system. However, in conducting research, there will be close collaboration with AUT company through design, production, and testing. The outcome of this research is to upgrade AUT company from tier 2 manufacturer (TRL 8-9) to tier 1 manufacturer (TRL 7-8) which will be served the Thailand competitiveness enhancing strategic goal.
คณะบริหารธุรกิจ
BrushXchange is a toothbrush brand dedicated to reducing plastic waste in Thailand by offering toothbrushes made from recycled plastic with replaceable bristles. These products help minimize waste generated by traditional toothbrushes. The design is modern and user-friendly, emphasizing durability, comfort, and affordability, making it appropriate for health-conscious and environmentally aware consumers. The brand aims to drive change in the oral care industry by providing high-quality products at accessible prices. Its marketing strategy focuses on using social media platforms like Instagram and TikTok and collaborating with organizations that promote sustainability. The product is distributed through retail stores such as Lotus’s and Tops. BrushXchange also prioritizes environmental responsibility by using recycled paper packaging and organizing sustainability campaigns. The brand's long-term goal is to become a widely recognized brand image in the eco-friendly toothbrush market in Thailand while encouraging sustainable living habits within society.