This study aims to develop alginate-based hydrogels reinforced with carrageenan and gellan gum as composite materials for oral drug delivery. Alginate, a naturally derived polymer from brown algae, forms a gel upon exposure to cations such as calcium ions, enhancing the hydrogel’s structural integrity. Carrageenan and gellan gum, both polysaccharides, further improve stability and encapsulation efficiency. This research investigates the physical properties, mechanical strength, encapsulation capacity, and swelling behavior of hydrogel beads under simulated gastrointestinal conditions. The findings are expected to demonstrate that incorporating carrageenan and gellan gum enhances the durability and stability of hydrogel beads while enabling controlled release of active compounds in the gastrointestinal tract. These advanced hydrogel beads hold significant potential for applications in the food and pharmaceutical industries as effective oral delivery systems for bioactive substances.
ในงานวิจัยนี้มีจุดมุ่งหมายเพื่อพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัม โดยมีคุณสมบัติที่ช่วยเสริมความแข็งแรงและความยืดหยุ่นให้กับโครงสร้างของไฮโดรเจลบีดส์ เพื่อเพิ่มความทนทานและเสถียรภาพมากขึ้น ซึ่งสามารถนำมาใช้ในการห่อหุ้มและปกป้องสารสำคัญ โดยมุ่งเน้นการควบคุมการปลดปล่อยสารสำคัญไปยังจุดเป้าหมาย การศึกษานี้จะครอบคลุมถึงลักษณะทางกายภาพ ความแข็งแรงของไฮโดรเจลบีดส์ และความสามารถในการกักเก็บสารสำคัญ ลักษณะทางกายภาพและการบวม (Swelling) ภายใต้สภาวะจำลองทางเดินอาหาร โดยใช้สารจำลองน้ำย่อยทั้งในกระเพาะอาหารและลำไส้ การพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัมมีศักยภาพในการนำไปใช้งานในอุตสาหกรรมเภสัชกรรมและอาหารที่ต้องการห่อหุ้มสารสำคัญที่มีประสิทธิภาพสูงในอนาคต
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
When it comes to the general perception of death, it is often seen as something negative or inauspicious. However, the end or death of someone can sometimes be the beginning of change, influencing thoughts, lifestyles, and attitudes in a positive way for those around them. For students aged 13-18, accessing and understanding this topic remains a challenge. Most available information is often presented in complex forms that are difficult for young people to grasp. Moreover, teaching materials in schools often lack creativity and engagement, leading to a decline in students’ interest in this subject. To address this issue, a website has been designed as an accessible and creative resource. It aims to deepen young people's understanding of the impact of actions and the death of individuals on the world they live in, while inspiring them to become part of creating positive change for the future.
คณะอุตสาหกรรมอาหาร
Fish gelatin is increasingly recognized as an alternative source of gelatin, but its use has been limited due to weak gelling properties. To address these issues, the effect of furcellaran, a gelling agent, was examined at various levels (25-100% FG substitution) on the structural and physicochemical properties of FG gels. As the amount of FUR increased to 25%, the FG/FUR gel showed improved hardness and gel strength (P<0.05). Additionally, increasing FUR levels led to higher gelling and melting points, showing a dose-dependent relationship. Microstructural analysis revealed that adding FUR created a denser gel network with smaller gaps. SAXS scattering intensities also increased as FUR concentration rose. Overall, adding FUR improved the gelling properties of FG without negatively affecting springiness and syneresis, enhancing gel strength and gelling temperature.
คณะเทคโนโลยีการเกษตร
Climate change and the increasing unpredictability of environmental conditions have aggravated the shortage of animal feed crops during the dry season. This study examines effect of packaging thickness on the quality of corn silage during long-term storage, to maintain its nutritional value during feed shortages. The results show that packaging with thicknesses of 80, 120, 150, and 200 microns effectively maintain good physical quality, including odor, texture, color, and pH levels, during the 0–21day storage period. The silage had a fermented like fruit flavor or vinegar flavor, a silage texture, and well-preserved leaves and stems. Its color remained yellowish-green, with pH values between 3.7 and 4.7. Additionally, lactic acid analysis found that silage in 200-micron-thick packaging for 21 days had the highest lactic acid content (5.64%). However, there were no significant differences in the nutritional value of the silage across different packaging thicknesses