This study aims to develop alginate-based hydrogels reinforced with carrageenan and gellan gum as composite materials for oral drug delivery. Alginate, a naturally derived polymer from brown algae, forms a gel upon exposure to cations such as calcium ions, enhancing the hydrogel’s structural integrity. Carrageenan and gellan gum, both polysaccharides, further improve stability and encapsulation efficiency. This research investigates the physical properties, mechanical strength, encapsulation capacity, and swelling behavior of hydrogel beads under simulated gastrointestinal conditions. The findings are expected to demonstrate that incorporating carrageenan and gellan gum enhances the durability and stability of hydrogel beads while enabling controlled release of active compounds in the gastrointestinal tract. These advanced hydrogel beads hold significant potential for applications in the food and pharmaceutical industries as effective oral delivery systems for bioactive substances.
ในงานวิจัยนี้มีจุดมุ่งหมายเพื่อพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัม โดยมีคุณสมบัติที่ช่วยเสริมความแข็งแรงและความยืดหยุ่นให้กับโครงสร้างของไฮโดรเจลบีดส์ เพื่อเพิ่มความทนทานและเสถียรภาพมากขึ้น ซึ่งสามารถนำมาใช้ในการห่อหุ้มและปกป้องสารสำคัญ โดยมุ่งเน้นการควบคุมการปลดปล่อยสารสำคัญไปยังจุดเป้าหมาย การศึกษานี้จะครอบคลุมถึงลักษณะทางกายภาพ ความแข็งแรงของไฮโดรเจลบีดส์ และความสามารถในการกักเก็บสารสำคัญ ลักษณะทางกายภาพและการบวม (Swelling) ภายใต้สภาวะจำลองทางเดินอาหาร โดยใช้สารจำลองน้ำย่อยทั้งในกระเพาะอาหารและลำไส้ การพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัมมีศักยภาพในการนำไปใช้งานในอุตสาหกรรมเภสัชกรรมและอาหารที่ต้องการห่อหุ้มสารสำคัญที่มีประสิทธิภาพสูงในอนาคต
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
In the world of blood donation, there are 2 types of people: those who donate blood and those who don't. Most campaigners emphasize how to persuade more people to donate blood and recruit more new blood donors. We believe that even though such focus is important, there're more critical aspects that might have been neglected, which is: for those who have already made up their minds to be blood doners, will they be successful in donating when the time comes? According to our studies, only 63 % of attempted doners are successful. Regrettably, 37 % has to go home disappointed as their bodies are not fit for the conditions required by Red Cross medical staff at blood donation centers (which include some most basic preparations such as low-fat food intake and 8-hours sleep on the night before). Our campaign, ‘Blood in Need, Buddy Indeed’, focuses on 2 aspects. Firstly, to persuade more people to donate blood. Secondly, for those who have made up their minds to donate blood, we will provide necessary support (both body and mind) so that they are fully prepared and successful in donating blood when the time comes via networks of systems, staffs and the newly designed and prototype of the application ‘Blood D’. Our campaign covers the whole ‘before/during/after’ experience of users (as blood doners). Support includes assessment of their current condition whether they are within the requirement of Red Cross Blood Bank. ‘Blood D’ will also provide relevant information on blood donating events, such as locations, and time booking. Once sign-up, the application “Blood D” will sent friendly reminder and clear infographic on how to prepare their bodies as daily notifications during the 7 days countdown. This is to ensure that the users’ blood will be ‘D’ (homophone of the Thai word ‘ดี’ which mean ‘good’ and at the same time playing on the word ‘ Buddy’) or be the ‘good blood’ that can save lives for those in need. After organizing 4 blood donation events both within and outside the KMITL. The numbers of successful blood doners have increased from 63 % to 78 % (this number is the average of 4 events, with the most successful event of 89%). The campaign has won the first runner up in national blood donation campaign competition. It is highly anticipated that once the application “Blood D” is fully launched, it will help increase the amount of blood collected up to 15% with the same numbers of existing doners.
คณะอุตสาหกรรมอาหาร
The consumption of plant-based products has been gaining popularity as consumers become more health-conscious and aware of environmental impacts. The food industry has been developing meat analogs with properties similar to conventional meat. This study investigates the chemical and physical properties of chickpea-based meat analog burgers and hybrid burgers containing both chickpeas and pork, using the sous-vide cooking method. This technique helps maintain food quality in terms of texture, moisture retention, and nutritional value. The experiment examined various properties of both types of burgers, including cooking loss, water holding capacity, shear force, pH value, and color analysis. Additionally, sensory evaluation was conducted to assess taste, texture, and overall consumer preference. The findings will provide insights into the optimal sous-vide conditions for producing plant-based and hybrid burgers with desirable quality characteristics that meet the needs of health-conscious consumers. This study serves as a valuable guideline for the food industry in developing high-nutritional-value alternative protein products while reducing meat consumption. By incorporating plant-based ingredients, it helps minimize environmental impact and promotes sustainability in food production. The research is significant in both food science and the development of healthier, competitive food products for the future market.
คณะบริหารธุรกิจ
The goal of the processed pineapple study is to reduce the number of pineapples wasted as a result of climate change and to determine the best way for processing different pineapple species. The drying method, also known as dehydration, is chosen for processing because it is appropriate for the variety's features and will provide the maximum benefit while reducing waste, resulting in the most value for the product. This study was carried out to develop the processing of new kinds, use various processing principles to adapt to this pineapple variety, raise the value of agricultural goods, significantly reduce waste, and provide marketing potential in the future.