This study aims to develop alginate-based hydrogels reinforced with carrageenan and gellan gum as composite materials for oral drug delivery. Alginate, a naturally derived polymer from brown algae, forms a gel upon exposure to cations such as calcium ions, enhancing the hydrogel’s structural integrity. Carrageenan and gellan gum, both polysaccharides, further improve stability and encapsulation efficiency. This research investigates the physical properties, mechanical strength, encapsulation capacity, and swelling behavior of hydrogel beads under simulated gastrointestinal conditions. The findings are expected to demonstrate that incorporating carrageenan and gellan gum enhances the durability and stability of hydrogel beads while enabling controlled release of active compounds in the gastrointestinal tract. These advanced hydrogel beads hold significant potential for applications in the food and pharmaceutical industries as effective oral delivery systems for bioactive substances.
ในงานวิจัยนี้มีจุดมุ่งหมายเพื่อพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัม โดยมีคุณสมบัติที่ช่วยเสริมความแข็งแรงและความยืดหยุ่นให้กับโครงสร้างของไฮโดรเจลบีดส์ เพื่อเพิ่มความทนทานและเสถียรภาพมากขึ้น ซึ่งสามารถนำมาใช้ในการห่อหุ้มและปกป้องสารสำคัญ โดยมุ่งเน้นการควบคุมการปลดปล่อยสารสำคัญไปยังจุดเป้าหมาย การศึกษานี้จะครอบคลุมถึงลักษณะทางกายภาพ ความแข็งแรงของไฮโดรเจลบีดส์ และความสามารถในการกักเก็บสารสำคัญ ลักษณะทางกายภาพและการบวม (Swelling) ภายใต้สภาวะจำลองทางเดินอาหาร โดยใช้สารจำลองน้ำย่อยทั้งในกระเพาะอาหารและลำไส้ การพัฒนาไฮโดรเจลบีดส์จากอัลจิเนตที่เสริมด้วยคาร์ราจีแนนและเจลแลนกัมมีศักยภาพในการนำไปใช้งานในอุตสาหกรรมเภสัชกรรมและอาหารที่ต้องการห่อหุ้มสารสำคัญที่มีประสิทธิภาพสูงในอนาคต
คณะเทคโนโลยีการเกษตร
Climate change affects agricultural systems worldwide, including Thailand, and may lead to reduced crop yields, impacting food security. Bambara groundnut is a crop with the potential to adapt to changing environments and can thrive in areas with limited resources. This research aims to study the impact of climate change on Bambara groundnut yields in Thailand using the DSSAT (Decision Support System for Agrotechnology Transfer) model, an important tool for predicting plant growth under various environmental conditions. This study utilizes climate data, soil composition, and genetic information of Bambara groundnut to simulate and analyze yield trends under future climate scenarios. Four study areas in Thailand were selected: Songkhla, Lampang, Yasothon, and Saraburi. The CSM-CROPGRO-Bambara groundnut model was used to assess the impact of changing temperature and rainfall on the growth and yield of Bambara groundnut. The results of this study are expected to provide farmers and researchers with valuable information for planning cultivation and managing peanut production in response to climate change. Additionally, the findings can help formulate policy guidelines to promote the cultivation of climate-resilient crops and support the country's food security.
คณะเทคโนโลยีสารสนเทศ
The AfterDay Horizon project is a two-player survival game developed to raise awareness of the impact of climate change. It leverages Virtual Reality (VR) technology and a website as gaming platforms. In the game, players experience a world where civilization has collapsed due to global warming, forcing the remaining population to live in bunkers to avoid environmental dangers. AfterDay Horizon focuses on collaboration between the two players to complete various missions that help the bunker’s inhabitants survive as long as possible. These missions are designed to encourage teamwork and decision-making in challenging scenarios, while also raising awareness of the potential consequences of climate change if left unresolved. Preliminary testing of the game showed that players successfully completed the missions and worked well together. However, some missions were complex and time-consuming, indicating areas for improvement to enhance the overall enjoyment and gameplay experience.
คณะวิศวกรรมศาสตร์
The design and development of an electric locomotive for the TRRN Railway Challenge 2025 aims to enhance learning potential and apply various theories in practical settings. The focus is on developing the locomotive to pass various tests, including acceleration, automatic braking system, noise, vibration, energy consumption, and durability throughout the competition. Additionally, the project helps improve skills in writing engineering design reports, which enables students to develop their analytical and discussion abilities in order to successfully complete each test according to the competition rules.