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คณะวิทยาศาสตร์
Atopic dermatitis patients are the second largest number among skin disease patients. There is no cure for atopic dermatitis, and it can only be treated to relieve symptoms, causing chronic disease. There is a chance that opportunistic infections will enter and cause more disease from the patient's wound, causing the patient to have complications from other infections. This study is interested in studying the reduction of the chance of opportunistic infections in patients with atopic dermatitis using natural extracts. The interest is in Plu Kaow and long pepper because there is data supporting the inhibition of microorganisms. The leaves of both plants are crudely extracted, soaked in 95% ethanol for 7 days, filtered with a Buchner filter, and the extracts are tested for phytochemicals to analyze phenolic components, flavonoids, tannins, anthocyanin, DPPH, and tested for antimicrobial properties. The experiments consisted of 5 types of gram-positive and gram-negative bacteria: E. coli, Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis. The researcher expects that this can be further developed and used to treat patients with atopic dermatitis.
คณะเทคโนโลยีการเกษตร
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วิทยาลัยการจัดการนวัตกรรมและอุตสาหกรรม
Diabetes is a significant global health issue, particularly due to complications related to diabetic wounds. Studies indicate that approximately 15-25% of diabetic patients develop foot ulcers, with more than 50% of severe cases leading to amputation. This results in a substantial decline in the quality of life for patients. Current treatments for diabetic wounds face challenges such as antibiotic-resistant bacterial infections and delayed wound healing, highlighting the need for innovative solutions to accelerate the healing process and reduce the risk of limb loss. Cotylelobium lanceolatum Craib, a medicinal plant long utilized in traditional Thai medicine, is known for its anti-inflammatory and wound-healing properties. This study focuses on developing an extract from Cotylelobium lanceolatum Craib in the form of nano silver (Nano Silver) to enhance the effectiveness of diabetic wound treatment. Nano silver technology enables deeper penetration into the skin, provides potent antibacterial activity, and promotes wound healing by reducing inflammation and stimulating tissue regeneration. The development of nano silver derived from Cotylelobium lanceolatum Craib extract is expected to help reduce chronic wounds in diabetic patients, lower the risk of infection, and decrease the incidence of limb amputation and mortality associated with diabetic wound complications. This research represents a significant step toward creating a safer and more effective treatment alternative for diabetic wound care.