The synthesis using electrons as reagents instead of oxidants is a method for synthesizing drug molecules in a way that reduces the use of chemicals, thereby minimizing environmental pollution.
การสังเคราะห์ทางอิเล็กโทรออร์แกนิกเป็นวิธีที่มีนวัตกรรม ช่วยส่งเสริมความยั่งยืน ประสิทธิภาพ และความแม่นยำในอุตสาหกรรมเคมี
คณะแพทยศาสตร์
This study explores the application of deep convolutional neural networks (CNNs) for accurate pill identification, addressing the limitations of traditional human-based methods. Using a dataset of 1,250 images across 10 household remedy drugs, various CNN architectures, including YOLO models, were tested under different conditions. Results showed that natural lighting was optimal for imprinted pills, while a lightbox improved detection for plain pills. The YOLOv5-tiny model demonstrated the best detection accuracy, and efficientNet_b0 achieved the highest classification performance. While the model showed strong results, its generalization is limited by sample size and drug variability. Nonetheless, this approach holds promise for enhancing medication safety and reducing errors in outpatient care.
คณะครุศาสตร์อุตสาหกรรมและเทคโนโลยี
Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang has a vision for sustainable excellence. The mission is to develop learners to be ready for the digital world, develop educational innovations using research as a base, strategic management with good governance, and academic services that benefit society. In this activity, the group of students joined with the Embassy of the Russian Federation in the Kingdom of Thailand, the working group of the Thai Silk and Culture Promotion Association, and the working group of the National Research Office (NRCT) to integrate knowledge to design a silk outfit that combines Thai and Russian cultures, create a network of cooperation in arts, culture, technology, innovation, and dissemination of knowledge and the beauty of Thai silk. The objective is to develop the potential of teachers and students in creative design, listen to the work guidelines from the working group of the Thai Silk and Culture Promotion Association, the working group of the National Research Office (NRCT) via an online meeting. The team of teachers and students from King Mongkut's Institute of Technology Ladkrabang under the name of the "Love Silk" group designed a Thai silk outfit that combines cultures with the identity of Thai silk and studying traditions and cultures of the Russian Federation's clothing. They studied related literature and research documents and integrated knowledge into the design process, inspired by the concept of the Rajapataen outfit. Since the reign of King Chulalongkorn (Rama V) in 1872, together with the clothing culture of the Russian Federation, emphasizing Thai silk, this concept has gone through the process of creating and selecting the design concept (Concept Generation and Selection). The concept received from the embassy was first submitted for feedback on July 25, 2024. There was a suggestion to add more uniqueness to Thai silk through a fashion show presentation by the wife and grandson of the Ambassador of the Russian Federation. Therefore, the designed outfits are 1 set of women's clothes and 1 set of boys' clothes. The women's set has an inner shirt adapted from the royal outfit using silk fabric, Kon Ka-ed pattern, with two separate pieces: 1 shirt and 1 skirt. The jacket is a modified long suit style, plain silk, dark pink and red. The boys' set has a long-sleeved shirt adapted from the contemporary royal style, tailored with cream silk, long slacks tailored with raw betel silk, and a collarless coat with blue silk and lotus pattern. Adapted from the Rajapattan suit with a long collar in an international style. On August 2, 2024, the designed suit and the prototype of the raw fabric suit were brought to the ambassador's wife and nephew to try on. On August 30, 2024, the ambassador was met for the 4th time to bring the silk suit that was cut into a real silk suit. The shirt was given to the ambassador's wife and nephew to try on. It was worn to join the fashion show in the 13th "Thai Silk to the World" Silk Festival at the Naval Auditorium, where lecturers and students from the Faculty of Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang, joined the fashion show in the finale round, which proceeded smoothly. After the event, the working group of the Thai Silk and Culture Promotion Association brought the clothes designed and tailored by the "Rak Prae Mai" team to exhibit Thai Silk to the World Exhibition from September 1-8, 2024 at the Emsphere Shopping Mall. The team summarized the report and compiled a complete report. In the implementation of this project, the Faculty of Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang has received support and facilitation throughout the project. The budget support from the National Research Council of Thailand (NRCT), the support of fabrics for sewing from the Thai Silk and Culture Promotion Association, and the information for designing valuable silk dresses from the Embassy of the Russian Federation in the Kingdom of Thailand are very important factors that made this operation a success. It is a very important experience for the team of teachers and students of Industrial Education and Technology, King Mongkut's Institute of Technology Ladkrabang. We sincerely hope to receive good cooperation in the future.
คณะทันตแพทยศาสตร์
Aggregatibacter actinomycetemcomitans is a key pathogen in periodontal disease, damaging periodontal ligaments and alveolar bone through biofilm formation. D-LL-31, an engineered antimicrobial peptide, exhibits superior biofilm-killing ability compared to conventional treatments, while DNase I enhances its efficacy by disrupting the biofilm matrix. This study evaluated the combined effects of D-LL-31 and DNase I on A. actinomycetemcomitans biofilms. Results showed that D-LL-31 effectively eradicated biofilms, and its combination with DNase I further enhanced biofilm disruption without cytotoxicity to gingival epithelial cells. The D-LL-31 and DNase I combination shows potential for development as a mouthwash to improve oral health and combat periodontal disease.