This project has been developed to address medical challenges related to the process of counting and classifying blood cells from samples, a task that requires both time and high precision. To reduce the workload of medical personnel, the developers have created a platform and an artificial intelligence (AI) system capable of automatically classifying and counting cells from sample images. This system is designed to assist medical laboratory technicians by enabling them to work more efficiently and accurately, reducing the time required for analysis. Furthermore, it promotes the advancement of medical technology, ensuring effective usability from classrooms and laboratories to hospitals.
เนื่องจากคณะผู้จัดทำมีโอกาสได้พูดคุยกับบุคลากรที่ทำงานในสายอาชีพเทคนิคการแพทย์ จึงเล็งเห็นถึงปัญหาด้านระยะเวลาการทำงาน โดยเฉพาะในกระบวนการแยกและนับจำนวนเซลล์เม็ดเลือด ซึ่งเป็นขั้นตอนที่ใช้เวลาค่อนข้างมาก คณะผู้จัดทำจึงเล็งเห็นโอกาสในการนำความรู้ที่มีมาพัฒนาแนวทางใหม่เพื่อช่วยลดภาระงานของบุคลากรทางการแพทย์ หากสามารถลดระยะเวลาในกระบวนการดังกล่าวได้ ด้วยเหตุนี้เอง โครงการนี้จึงถูกริเริ่มขึ้นมา โดยมีเป้าหมายเพื่อพัฒนาเทคโนโลยีที่สามารถสนับสนุนการทำงานของบุคลากรทางการแพทย์ และยกระดับคุณภาพของกระบวนการตรวจวินิจฉัยให้มีความรวดเร็วและแม่นยำยิ่งขึ้น
คณะวิศวกรรมศาสตร์
Motor control is a critical process for muscle contraction, which is initiated by nerve impulses governed by the motor cortex. This process is vital for performing activities of daily living (ADLs). Consequently, a disruption in communication between the brain and muscles, as seen in various chronic conditions and diseases, can impair bodily movement and ADLs. Evaluating the interaction between brain function and motor control is significant for the diagnosis and treatment of motor control disorders; moreover, it can contribute to the development of brain-computer interfaces (BCIs). The purpose of this study is to investigate brain activation in designed upper extremity motor control tasks in regulating the pushing force in different brain regions; and develop investigation methods to assess motor control tasks and brain activation using a robotic arm to guide upper extremity force and motor control. Eighteen healthy young adults were asked to perform upper extremity motor control tasks and recorded the hemodynamic signals. Functional Near-Infrared Spectroscopy (fNIRs) and robotic arms were used to assess brain activation and the regulation of pushing force and extremity motor control. Two types of motion, static and dynamic, move along a designated trajectory in both forward and backward directions, and three different force levels selected from a range of ADLs, including 4, 12, and 20 N, were used as force-regulating upper extremity motor control tasks. The hemodynamic responses were measured in specific regions of interest, namely the primary motor cortex (M1), premotor cortex (PMC), supplementary motor area (SMA), and prefrontal cortex (PFC). Utilizing a two-way repeated measures ANOVA with Bonferroni correction (p < 0.00625) across all regions, we observed no significant interaction effect between force levels and movement types on oxygenated hemoglobin (HbO) levels. However, in both contralateral (c) and ipsilateral (i) PFC, movement type—static versus dynamic—significantly affected brain activation. Additionally, cM1, iPFC, and PMC showed a significant effect of force level on brain activation.
คณะอุตสาหกรรมอาหาร
The "PRIVARY" product is an innovative herbal jelly beverage designed to support weight management and promote health through the benefits of four Thai herbs: roselle, safflower, chrysanthemum, and bitter melon. These herbs are rich in active compounds such as flavonoids, beta-carotene, and anthocyanins, which help reduce blood lipids, prevent inflammation, and exhibit antioxidant properties. The product emphasizes convenience and caters to health-conscious consumers using advanced production techniques like Inverse and External Gelation to create spheres encapsulating key bioactive compounds. Additionally, the product aligns with sustainability goals by enhancing the value of Thai herbs and supporting local communities.
คณะวิทยาศาสตร์
Listeriosis is a severe foodborne illness characterized by a fatality rate exceeding 30%, attributed to the pathogen Listeria monocytogenes. This study evaluated 160 lactic acid bacteria (LAB) isolated from Thai pickled crabs for their potential as agents against L. monocytogenes and for their probiotic properties and probiogenomic characteristics. Among these strains, strain DRC3-2 exhibited activity through the synthesis of bacteriocin DRC3-2, which significantly inhibited L. monocytogenes ATCC 19115 in spot-on-lawn assays. Phenotypic and whole-genome analyses revealed that strain DRC3-2 thrived in environments with 2-6% NaCl, pH values ranging from 3 to 9, and temperatures between 25 and 45°C. Based on average nucleotide identity (ANI) and digital DNA‒DNA hybridization (dDDH) values, strain DRC3-2 was taxonomically classified as Lactococcus lactis subsp. hordinae. The production of bacteriocin DRC3-2 peaked during the late stationary phase, following its synthesis in the early exponential growth phase. BAGEL4 analysis identified the putative novel bacteriocin DRC3-2 as lactococcin A and B, with respective bit-scores of 40.05 and 36.58. In silico safety assessments confirmed the nonpathogenic nature of strain DRC3-2 in humans, highlighting its absence of antibiotic resistance genes. Finally, this investigation underscores the novel bacteriocin DRC3-2 for application in the prevention and treatment of L. monocytogenes infections.