Stirling engine is the external heated engine that heat is sup-plied externally to the heater part of the engine. Thus, Stirling cycle engine can be employed with various sources of renewable energy such as biomass, biofuel, solar energy, geothermal energy, recovery heat, and waste. The integration of gasifier, burner, and heat engine as a power system offers more fuel choices of each local area with potential resources resulting independent from shortage and cost fluctuation of fossil fuel. This research aims to investigate the integration of the Stirling engine with a wood pellet gasifier for electric power generation. Biomass can be controlled to have continuously combustion with ultra-low toxic emission. Stirling engine, therefore, is a promising alternative in small-scale-electricity production. Even though many biomass-powered Stirling engines were successfully constructed and marketed but these engines and the use of biomass resources as fuel for power generation are quite new concepts in some developing countries. Especially, the capital cost of this engine is high and unaffordable for installation compared to other power systems. Therefore, this research aims to the study attractive and feasibility of the compact Stirling engine with green energy.
เนื่องจากความต้องการพลังงานที่มีมากขึ้น แต่เชื้อเพลิงฟอสซิลซึ่งเป็นแหล่งพลังงานหลักมีอยู่อย่างจำกัดและเป็นสาเหตุหนึ่งของมลพิษและภาวะโลกร้อน ดังนั้นพลังงานทางเลือกจึงเป็นกุญแจสำคัญเพื่อความยั่งยืนด้านพลังงาน ประเทศไทยมีศักยภาพของพลังงานชีวมวลจากเกษตรกรรม ดังนั้นการพัฒนาระบบผลิตไฟฟ้าที่มลพิษต่ำและสามารถใช้ได้กับแหล่งพลังงานทดแทนจึงจำเป็นอย่างยิ่ง โดยเฉพาะเครื่องยนต์สเตอร์ลิงซึ่งมีโครงสร้างชิ้นส่วนไม่ซับซ้อน ปราศจากการสันดาปภายในเครื่องยนต์จึงเป็นเครื่องยนต์ที่มีศักยภาพผลิตไฟฟ้าด้วยพลังงานสะอาดและเป็นมิตรกับสิ่งแวดล้อมและความสำเร็จของโรงไฟฟ้าเครื่องยนต์สเตอร์ลิง ในประเทศไทย เพื่อคนไทย
คณะบริหารธุรกิจ
BrushXchange is a toothbrush brand dedicated to reducing plastic waste in Thailand by offering toothbrushes made from recycled plastic with replaceable bristles. These products help minimize waste generated by traditional toothbrushes. The design is modern and user-friendly, emphasizing durability, comfort, and affordability, making it appropriate for health-conscious and environmentally aware consumers. The brand aims to drive change in the oral care industry by providing high-quality products at accessible prices. Its marketing strategy focuses on using social media platforms like Instagram and TikTok and collaborating with organizations that promote sustainability. The product is distributed through retail stores such as Lotus’s and Tops. BrushXchange also prioritizes environmental responsibility by using recycled paper packaging and organizing sustainability campaigns. The brand's long-term goal is to become a widely recognized brand image in the eco-friendly toothbrush market in Thailand while encouraging sustainable living habits within society.
คณะแพทยศาสตร์
Background: The RGL3 gene plays a role in key signal transduction pathways and has been implicated in hypertension risk through the identification of a copy number variant deletion in exon 6. Genome-wide association studies have highlighted RGL3 as associated with hypertension, providing insights into the genetic underpinnings of the condition and its protective effects on cardiovascular health. Despite these findings, there is a lack of data that confirms the precise role of RGL3 in hypertension. Additionally, the functional impact of certain variants, particularly those classified as variants of uncertain significance, remains poorly understood. Objectives: This study aims to analyze alterations in the RGL3 protein structure caused by mutations and validate the location of the ligand binding sites. Methods: Clinical variants of the RGL3 gene were obtained from NCBI ClinVar. Variants of uncertain significance and likely benign were analyzed. Multiple sequence alignment was conducted using BioEdit v7.7.1. AlphaFold 2 predicted the wild-type and mutant 3D structures, followed by quality assessment via PROCHECK. Functional domain analysis of RasGEF, RASGEF_NTER, and RA domains was performed, and BIOVIA Discovery Studio Visualizer 2024 was used to evaluate structural and physicochemical changes. Results: The analysis of 81 RGL3 variants identified 5 likely benign and 76 variants of uncertain significance (VUS), all of which were missense mutations. Structural modeling using AlphaFold 2 revealed three key domains: RasGEF_NTER, RasGEF, and RA, where mutations induced conformational changes. Ramachandran plot validation confirmed 79.7% of residues in favored regions, indicating an overall reliable structure. Moreover, mutations within RasGEF and RA domains altered polarity, charge, and stability, suggesting potential functional disruptions. These findings provide insight into the structural consequences of RGL3 mutations, contributing to further functional assessments. Discussion & Conclusion: The identified RGL3 mutations induced physicochemical alterations in key domains, affecting charge, polarity, hydrophobicity, and flexibility. These changes likely disrupt interactions with Ras-like GTPases, impairing GDP-GTP exchange and cellular signaling. Structural analysis highlighted mutations in RasGEF and RA domains that may interfere with activation states, potentially affecting protein function and stability. These findings suggest that mutations in RGL3 could have functional consequences, emphasizing the need for further molecular and functional studies to explore their pathogenic potential.
คณะวิศวกรรมศาสตร์
A high-pressure gas storage tank made from composite materials, including carbon fiber, resin, and plastic, is designed for storing compressed natural gas (CNG) or hydrogen. This type of tank is classified as a Type IV high-pressure vessel. In this research, it is designed to operate at a pressure of 250 bar for the transportation of compressed natural gas.