This research aims to investigate the adulteration of Khao Dawk Mali 105 rice based on storage age using Near-Infrared Spectroscopy (NIRS) with Fourier Transform Near-Infrared Spectroscopy (FT-NIR) in the wavenumber range of 12,500 – 4,000 cm-1 (800 – 2,500 nm). Storage duration significantly impacts the quality of cooked rice. This research is divided into two parts: 1) to investigate the feasibility of separating rice according to storage age (1, 2, and 3 years) using the best model created by an Ensemble method combined with Second Derivative, which achieved an accuracy of 96.3%. 2) To investigate adulteration based on storage age by adulterating at 0% (all 2- and 3-year-old rice), 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, and 100% (all 1-year-old rice). The best model was created using Gaussian Process Regression (GPR) combined with Smoothing + Multiplicative Scatter Correction (MSC), with coefficients of determination (r²), root mean square error of prediction (RMSEP), bias, and prediction ability (RPD) values of 0.92, 8.6%, 0.9%, and 3.6 respectively. This demonstrates that the adulteration model can be applied to separate rice by storage age (1, 2, and 3 years). Additionally, the color values of rice with different storage ages show differences in L* and b* values.
โรงงานผู้ผลิตข้าวพบปัญหาการปลอมปนของข้าวสารที่มีอายุการเก็บรักษาต่างกัน โดยทั่วไปการคัดแยกการปลอมปนจะใช้วิธีมาตรฐานโดยการหุงข้าว จากนั้นนำข้าวหุงสุกไปวัดเนื้อสัมผัสเพื่อแยกอายุของข้าว ซึ่งใช้เวลาและเป็นการทำลายตัวอย่างและเกิดความล่าช้าในการตรวจสอบคุณภาพข้าวสาร งานวิจัยนี้ใช้เทคนิคเนียร์อินฟราเรดสเปกโทรสโกปี (Near-Infrared Spectroscopy, NIRS) ในการตรวจสอบการปลอมปนของข้าวสารพันธุ์ขาวดอกมะลิ 105 (KDML 105) ที่อายุการเก็บรักษาต่างกันเพื่อแก้ไขปัญหาดังกล่าว
คณะบริหารธุรกิจ
Parking space shortages in urban areas contribute to traffic congestion, inefficient land use, and environmental challenges. Automated Parking Systems (APS) provide an innovative solution by optimizing space utilization, reducing search times, and minimizing carbon emissions. This research investigates key factors influencing user adoption of APS technology using the UTAUT2 framework, focusing on variables such as Performance Expectancy, Effort Expectancy, Social Influence, Trust in Technology, and Environmental Consciousness. The APS Evolution project presents a smart parking solution that enhances efficiency, minimizes environmental impact, and improves user experience in urban settings. The initiative emphasizes technology-driven urban mobility and sustainable parking management to align with the evolving needs of modern cities.
คณะวิศวกรรมศาสตร์
A platform that aims to connect students from all faculties and departments to promote joint activities and develop effective social and collaborative skills, focusing on: Promoting learning and self-development through reviewing lessons and collaborative learning that are relevant to all faculties and departments in the university, creating a space for negotiation and exchange of knowledge, and supporting joint activities to build relationships and cooperation among students.
คณะวิทยาศาสตร์
Cancer remains a major global health challenge as the second-leading cause of human death worldwide. The traditional treatments for cancer beyond surgical resection include radiation and chemotherapy; however, these therapies can cause serious adverse side effects due to their high killing potency but low tumor selectivity. The FDA approved monoclonal antibodies (mAbs) that target TIGIT/PVR (T-cell immunoglobulin and ITIM domain/poliovirus receptor) which is an emerging immune checkpoint molecules has been developed; however, the clinical translation of immune checkpoint inhibitors based on antibodies is hampered due to immunogenicity, immunological-related side effects, and high costs, even though these mAbs show promising therapeutic efficacy in clinical trials. To overcome these bottlenecks, small-molecule inhibitors may offer advantages such as better oral bioavailability and tumor penetration compared to mAbs due to their smaller size. Here, we performed structure-based virtual screening of FDA-approved drug repertoires. The 100 screened candidates were further narrowed down to 10 compounds using molecular docking, with binding affinities ranging from -9.152 to -7.643 kcal/mol. These compounds were subsequently evaluated for their pharmacokinetic properties using ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, which demonstrated favorable drug-like characteristics. The lead compounds will be further analyzed for conformational changes and binding stability against TIGIT through molecular dynamics (MD) simulations to ensure that no significant conformational changes occur in the protein structure. Collectively, this study represents the potential of computational methods and drug repurposing as effective strategies for drug discovery, facilitating the accelerated development of novel cancer treatments.