Innovation Owner
ผศ.ดร. Achara Lukkananukool
Advisor
Details
This research explores the use of Lactic acid bacteria (LAB) isolated from Thai livestock as a sustainable alternative to antibiotics. It aims to address issues like drug resistance and antibiotic residues by developing locally adapted probiotic prototypes.
This research provides a comprehensive overview of the use of antibiotics in livestock production, highlighting both the benefits and the risks associated with their use. The benefits, such as improving immunity, digestion, and reducing infections, are contrasted with the growing concern over antibiotic residues and the development of drug resistance.
Key aspects of the study include:
- Global Trends: Many countries, including the EU and Japan, have banned antibiotics as growth promoters, with others following suit.
- Thailand's Approach: Since September 2020, Thailand has strictly regulated antibiotic use in animal feed at both mills and farms.
- Probiotics as an Alternative: The study examines the potential of Lactic acid bacteria (LAB) found in the digestive tracts of Thai broilers, pigs, and cattle. This aims to overcome the low survival rates often seen in imported probiotic products.
Objective
The objectives are to isolate, identify, and evaluate Lactic acid bacteria for their lactic acid production, pathogen inhibition, antibiotic resistance profiles, and survival within the livestock digestive tract.
- To isolate and identify Lactic acid bacteria capable of producing lactic acid.
- To isolate and identify Lactic acid bacteria capable of inhibiting the growth of tested pathogenic bacteria.
- To test the antibiotic resistance of the isolated Lactic acid bacteria.
- To evaluate the tolerance of the bacteria to the conditions within the livestock digestive tract (in vitro).